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1, 4-Addition of Terminal Alkynes to Conjugated Enones in Water Using Green Catalyst Bis[(l)prolinato-N,O]Zn—An Environmentally Benign Protocol

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Abstract

An easy, low cost, and green procedure is proposed for the 1, 4-addition of terminal alkynes to conjugated enones in water as a sole medium using easily accessible Zn[(l)Proline]2. This protocol has advantages of high yield, mild reaction conditions, no environmental pollution and simple work up procedure.

Graphical Abstract

Recyclable Bis[(l)prolinato-N,O]Zn provides eminent, efficient, economical, environmentally benign protocol for the 1, 4-addition of terminal alkynes to conjugated enones in water as sole media. For the first time easily accessible, cheap catalyst was employed for such type of reaction.

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Acknowledgments

The authors (A. Jain and S. Bhardwaj) are thankful to UGC and CSIR, New Delhi for their junior research fellowship.

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Authors and Affiliations

  1. Green Research Laboratory, Department of Chemistry, University of Delhi, Delhi, 110007, India

    Mazaahir Kidwai, Arti Jain & Saurav Bhardwaj

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  1. Mazaahir Kidwai
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  2. Arti Jain
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  3. Saurav Bhardwaj
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Correspondence to Mazaahir Kidwai.

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Kidwai, M., Jain, A. & Bhardwaj, S. 1, 4-Addition of Terminal Alkynes to Conjugated Enones in Water Using Green Catalyst Bis[(l)prolinato-N,O]Zn—An Environmentally Benign Protocol. Catal Lett 141, 183–190 (2011). https://doi.org/10.1007/s10562-010-0451-8

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