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Ruthenium (III) Chloride as a Novel and Efficient Catalyst for the Synthesis of Substituted Pyrroles Under Solvent-Free Conditions

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Abstract

Paal-Knorr condensation of 2,5-hexadione with primary amines in the presence of a catalytic amount of RuCl3 under solvent-free conditions has been accomplished with an excellent yield. This method is very easy, rapid, and high yielding reaction for the synthesis N-substituted pyrrole derivatives.

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  1. Burnham Institute for Medical Research, 10901, North Torrey Pines Road, La Jolla, CA, 92037, USA

    Surya K. De

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  1. Surya K. De
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De, S.K. Ruthenium (III) Chloride as a Novel and Efficient Catalyst for the Synthesis of Substituted Pyrroles Under Solvent-Free Conditions. Catal Lett 124, 174–177 (2008). https://doi.org/10.1007/s10562-008-9461-1

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  • DOI: https://doi.org/10.1007/s10562-008-9461-1

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