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Stem cell-based therapy as a promising approach in Alzheimer's disease: current perspectives on novel treatment

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Abstract

Alzheimer's disease (AD) is a neuronal disorder with insidious onset and slow progression, leading to growing global concern with huge implications for individuals and society. The occurrence of AD has been increased and has become an important health issue throughout the world. In recent years, the care of more than 35 million patients with AD costs over $ 600 billion per year, it is approximately 1 percent of the global Gross Domestic Product. Currently, the therapeutic approach is not effective for neurological deficits especially after the development of these major neurological disorders. The discovery of the technique called cell-based therapy has shown promising results and made important conclusions beyond AD using the stem cells approach. Here we review recent progress on stem cell-based therapy in the context of AD.

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Acknowledgments

This work was supported by grants from the Vice Chancellor for Research and Technology, Kashan University of Medical Sciences, Kashan, Iran; and Shahid Beheshti University of Medical Sciences, Tehran, Iran; Saeid & Maryam.

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  1. Department of Physiology and Neurophysiology Research Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Saeid Bagheri-Mohammadi

  2. Department of Physiology, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran

    Saeid Bagheri-Mohammadi

  3. Department of Applied Cell Sciences, Faculty of Medicine, Kashan University of Medical Sciences, Kashan, Iran

    Saeid Bagheri-Mohammadi

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  1. Saeid Bagheri-Mohammadi
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Dr. SB-M design and prepare the paper; Saeid & Maryam.

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Correspondence to Saeid Bagheri-Mohammadi.

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Bagheri-Mohammadi, S. Stem cell-based therapy as a promising approach in Alzheimer's disease: current perspectives on novel treatment. Cell Tissue Bank 22, 339–353 (2021). https://doi.org/10.1007/s10561-020-09896-3

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