Cell and Tissue Banking

, Volume 17, Issue 4, pp 713–720 | Cite as

Reduced rates of non-union with modified periacetabular osteotomy using peracetic-acid sterilized cancellous allografts

  • Georgi I. WassilewEmail author
  • Viktor Janz
  • Lisa Renner
  • Carsten Perka
  • Axel Pruss


The objective of the present study was to analyze the clinical and radiological results of periacetabular osteotomies (PAO) using Kirschner wire fixation and an allogeneic cancellous bone graft. This retrospective cohort study included 73 patients (85 PAOs). The allografts were processed from distal femur of cadaveric donors, defatted, sterilized with a peracetic-acid ethanol solution and freeze-dried. The clinical outcome, as measured by the Harris Hip Scores (HHS), the complication rate and the acetabular correction, as measured by radiological parameters, were compared. The postoperative femoral head coverage and HSS were significantly improved. Major complications occurred in five cases (6 %), but in no case did we observe a non-union or a graft-associated adverse effect. Fixation of the acetabular fragment with Kirschner wires in combination with an allogeneic cancellous bone graft is a safe method, with a low complication rate, no loss of correction and can prevent the occurrence of non-union with a high degree of probability.


Periacetabular osteotomy Kirschner wire Allografts Peracetic acid Tissue bank 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Science+Business Media Dordrecht 2016

Authors and Affiliations

  • Georgi I. Wassilew
    • 1
    Email author
  • Viktor Janz
    • 1
  • Lisa Renner
    • 1
  • Carsten Perka
    • 1
  • Axel Pruss
    • 2
  1. 1.Orthopedics Department, Center for Musculoskeletal SurgeryCharité - Universitätsmedizin BerlinBerlinGermany
  2. 2.University Tissue Bank, Institute of Transfusion MedicineCharité - Universitätsmedizin BerlinBerlinGermany

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