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Cell and Tissue Banking

, Volume 15, Issue 3, pp 287–289 | Cite as

How can we improve tracking of transplanted tissue in the United States?

  • Reena Mahajan
  • Matthew J. KuehnertEmail author
Brief Communication

Abstract

Currently an estimated two million tissues are distributed for transplantation annually. With increasing use of recovered tissue, clusters of transplant-transmitted infection have shown the difficulty of tracking tissues from an infected donor to the recipient. The challenge of tissue tracking to multiple transplant recipients was illustrated in a recent investigation of transmission of hepatitis C virus infection from a donor of organs and tissues. When a tissue bank issued a recall of the donated tissue, the Centers for Disease Control and Prevention was notified to assist public health authorities; the mean time to locate and notify the physicians who had transplanted the tissue was 13 days, while the mean time to notify, inform, and test the patients was 29 days. Lack of common coding and nomenclature was one of the key challenges in tracking tissue to the recipient. Some changes that could improve timeliness in the event of a recall includes: (1) standardized tissue nomenclature and coding through unique donor identifiers; (2) tissue traceability requirements using systems similar to that used for blood products; (3) a surveillance system for adverse events that provides feedback at the provider level.

Keywords

Tissue Transplantation Tracking Safety 

Notes

Acknowledgments

The authors thank Susan Hocevar, MD, Division of Healthcare Quality Promotion, and Scott D Holmberg, MD, MPH, Division of Viral Hepatitis, Centers for Disease Control and Prevention for their assistance with this investigation.

Conflict of interest

No conflicts of interest have been declared for the authors on this manuscript.

References

  1. American Association of Tissue Banks (AATB) (2010) Annual survey of accredited tissue banks in the United States. AATB, McLean, VAGoogle Scholar
  2. Centers for Disease Control and Prevention (CDC) (2011) Transmission of hepatitis C virus through transplanted organs and tissues—Kentucky and Massachusetts, 2011. MMWR Morb Mortal Wkly Rep 60:1697–1700Google Scholar
  3. DePaolo JS, Barbeau JM (2013) Enhanced tracking of tissue for transplantation. JAMA 309:443–444PubMedCrossRefGoogle Scholar
  4. ICCBBA (2013) http://www.iccbba.org. Accessed October 4, 2013
  5. Kuehnert MJ, Yorita KL, Holman RC, Strong DM (2007) For the AABB Tissue task force. Human tissue oversight in hospitals: an AABB survey. Transfusion 47:194–200Google Scholar
  6. Strong DM, Seem D, Taylor G, Parker J, Stewart D, Kuehnert MJ (2010) Development of a transplantation transmission sentinel network to improve safety and traceability of organ and tissues. Cell Tissue Bank 11:335–343PubMedCrossRefGoogle Scholar
  7. The European Parliament and the Council of the European Union (2004) Official Journal of the European Union. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2004:102:0048:0058:en:PDF. Accessed October 4, 2013
  8. Warwick RM, Chapman J, Pruett TL, Wang H (2013) Globally consistent coding systems for medical products of human origin. Bull World Health Organ. http://www.who.int/bulletin/volumes/91/5/12-116988/en/index.html#.UYETS4dhdS8.email. Accessed May 1, 2013
  9. World Health Organization (2006) Second global consultation on regulatory requirements for human cells and tissues for transplantation: towards global harmonization through graduated standards. http://www.who.int/transplantation/2dHTTGHreport.pdf. Accessed February 26, 2013

Copyright information

© Springer Science+Business Media Dordrecht (outside the USA) 2013

Authors and Affiliations

  1. 1.Centers for Disease Control and PreventionAtlantaUSA
  2. 2.Division of Healthcare Quality PromotionNational Center for Emerging and Zoonotic Diseases, Centers for Disease Control and PreventionAtlantaUSA

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