Abstract
The menisci of the knee are two crescent shaped cartilage shock absorbers sitting between the femur and the tibia, which act as load sharers and shock absorbers. Loss of a meniscus leads to a significant increase in the risk of developing arthritis in the knee. Replacement of a missing meniscus with allograft tissue can reduce symptoms and may potentially reduce the risk of future arthritis. Meniscal allograft transplantation is a complex surgical procedure with many outstanding issues, including ‘what techniques should be used for processing and storing grafts?’, ‘how should the allografts be sized?’ and ‘what surgical implantation techniques might be most appropriate?’ Further clinical research is needed and close collaboration between the users (surgeons) and the suppliers (tissue banks) is essential. This review explores the above subject in detail.
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Arnoczky SP, McDevitt CA, Schmidt MB, Mow VC, Warren RF (1988) The effect of cryopreservation on canine menisci: a biochemical, morphologic, and biomechanical evaluation. J Orthop Res 6(1):1–12
Backer M (1999) Meniscus transplantation–consensus declaration [editorial]. Scand J of Med Sci Sports 9(3):131–133
Baker PE, Peckham AC, Pupparo F, Sanborn JC (1985) Review of meniscal injury and associated sports. Am J Sports Med 13:1–4
Baratz ME, Fu FH, Mengato R (1986) Meniscal tears: the effect of meniscectomy and of repair on intraarticular contact areas and stress in the human knee. Am J Sports Med 14:270–274
Bruns J, Kahrs J, Kampen J, Behrens P, Plitz W (1998) Autologous perichondral tissue for meniscal replacement. J Bone Joint Surg 80-B:918–923
Buck BE, Malinin TI, Brown MD (1989) Bone transplantation and human immunodeficiency virus. An estimate of risk of acquired immunodeficiency syndrome (AIDS). Clin Orthop Relat Res 240:129–136
Cameron JC, Saha S (1997) Meniscal allograft transplantation for unicompartmental arthritis of the knee. Clin Orthop Relat Res 337:164–171
Cheung DT, Perelman N, Tong D, Nimni ME (1990) The effect of gamma-irradiation on collagen molecules, isolated alpha-chains, and crosslinked native fibers. J Biomed Mater Res 24:581–589
Dienst M, Greis PE, Ellis BJ, Bachus KN, Burks RT (2007) Effect of lateral meniscal allograft sizing on contact mechanics of the lateral tibial plateau: an experimental study in human cadaveric knee joints. Am J Sports Med 35:34–42
Eastlund T, Strong DM (2003) Infectious disease transmissions through tissue transplantation. In: Phillips GO, Kearney JN, Strong DM, vonVersen R, Nather A (eds) Advances in tissue banking, vol 7. World Scientific, Singapore, pp 51–131
Elves MW (1976) Newer knowledge of the immunology of bone and cartilage. Clin Orthop Relat Res 120:232–259
Hamlet W, Liu SH, Yang R (1997) Destruction of a cyropreserved meniscal allograft: a case for acute rejection. Arthroscopy 13:517–521
Haut TL, Hull ML, Howell SM (2000) Use of roentgenography and magnetic resonance imaging to predict meniscal geometry determined with a three-dimensional coordinate digitizing system. J Orthop.Res 18:228–237
Johnson LL, Feagin JA Jr (2000) Autogenous tendon graft substitution for absent knee joint meniscus: a pilot study. Arthroscopy 16:191–196
Jones RS, Keene GC, Learmonth DJ, Bickerstaff D, Nawana NS, Costi JJ, Pearcy MJ (1996) Direct measurement of hoop strains in the intact and torn human meniscus. Clin Biomech 11:295–300
Kenny C, Krackow KA, McCarthy EF (1983) An evaluation of the effects of a silastic meniscus prothesis on post-meniscectomy osteoarthrosis. Trans Orthop Res Soc 8:335
Kohn D (1993) Autograft meniscus replacement: experimental and clinical results. Knee Surg Sports Traumatol Arthrosc 1:123–125
Kohn D, Wirth CJ, Reiss G, Plitz W, Maschek H, Erhardt W, Wulker N (1992) Medial meniscus replacement by a tendon autograft. Experiments in sheep. J Bone Joint Surg 74-B:910–917
Kohn D, Rudert M, Wirth CJ, Plitz W, Reiss G, Maschek H (1997) Medial meniscus replacement by a fat pad autograft. An experimental study in sheep. Int Orthop 21:232–238
Kotsovolos ES, Hantes ME, Mastrokalos DS, Lorbach O, Paessler HH (2006) Results of all-inside meniscal repair with the FasT-Fix meniscal repair system. Arthroscopy 22:3–9
McDermott ID, Amis AA (2006) The consequences of meniscectomy. J Bone Joint Surg 88-B:1549–1556
McDermott ID, Sharifi F, Bull AM, Gupte CM, Thomas RW, Amis AA (2004) An anatomical study of meniscal allograft sizing. Knee Surg Sports Traumatol Arthrosc 12:130–135
McDermott ID, Lie DT, Edwards A, Bull AMJ, Amis AA (2008) The effects of lateral meniscal allograft transplantation techniques on tibio-femoral contact pressures. Knee Surg Sports Traumatol Arthrosc 16:553–560
Messner K (1994) Meniscal substitution with a Teflon-periosteal composite graft: a rabbit experiment. Biomaterials 15:223–230
Milachowski KA, Weismeier K, Wirth CJ (1989) Homologous meniscus transplantation. Experimental and clinical results. Int Orthop 13:1–11
Pollard ME, Kang Q, Berg EE (1995) Radiographic sizing for meniscal transplantation. Arthroscopy 11:684–687
Rath E, Richmond JC, Yassir W, Albright JD, Gundogan F (2001) Meniscal allograft transplantation. Two- to eight-year results. Am J Sports Med 29:410–414
Rodkey WG, DeHaven KE, Montgomery WH III, Baker CL Jr, Beck CL Jr, Hormel SE, Steadman JR, Cole BJ, Briggs KK (2008) Comparison of the collagen meniscus implant with partial meniscectomy. A prospective randomized trial. J Bone Joint Surg 90-Am:1413–1426
Roos H, Lauren M, Adalberth T, Roos EM, Jonsson K, Lohmander LS (1998) Knee osteoarthritis after meniscectomy: prevalence of radiographic changes after twenty-one years, compared with matched controls. Arthritis Rheum 41:687–693
Sekaran SV, Hull ML, Howell SM (2002) Nonanatomic location of the posterior horn of a medial meniscal autograft implanted in a cadaveric knee adversely affects the pressure distribution on the tibial plateau. Am J Sports Med 30:74–82
Shaffer B, Kennedy S, Klimkiewicz J, Yao L (2000) Preoperative sizing of meniscal allografts in meniscus transplantation. Am J Sports Med 28:524–533
Sommerlath K, Gillquist J (1992) The effect of a meniscal prosthesis on knee biomechanics and cartilage. An experimental study in rabbits. Am J Sports Med 20:73–81
Stollsteimer GT, Shelton WR, Dukes A, Bomboy AL (2000) Meniscal allograft transplantation: a 1- to 5-year follow-up of 22 patients. Arthroscopy 16:343–347
Stone KR and Walgenbach A (2000) Surgical technique of meniscal replacement in arthritic knees. Presented at ESKKA 9th congress, 16–20 September 2000, London, UK
Stone KR, Freyer A, Turek T, Walgenbach AW, Wadhwa S, Crues J (2007) Meniscal sizing based on gender, height and weight. Arthroscopy 23:503–508
Verdonk PC, Demurie A, Almqvist KF, Veys EM, Verbruggen G, Verdonk R (2006) Transplantation of viable meniscal allograft. Surgical technique. J Bone Joint Surg 88-Am(Suppl 1 Pt 1):109–118
Veth RP, den-Heeten GJ, Jansen HW, Nielsen HK (1983) An experimental study of reconstructive procedures in lesions of the meniscus. Use of synovial flaps and carbon fiber implants for artificially made lesions in the meniscus of the rabbit. Clin Orthop Relat Res 181:250–254
Acknowledgment
The author wishes to thank Dr Ruth Warwick (NHSBT TS) for her advice and assistance with the preparation of this paper.
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McDermott, I.D. What tissue bankers should know about the use of allograft meniscus in orthopaedics. Cell Tissue Bank 11, 75–85 (2010). https://doi.org/10.1007/s10561-009-9127-2
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DOI: https://doi.org/10.1007/s10561-009-9127-2