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Iliac crest fresh frozen homografts used in pre-prosthetic surgery: a retrospective study

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Abstract

In the case of severe jaw atrophy several options are available to restore the alveolar crest. Aim of the present study was to evaluate the resorption over time of homologous fresh frozen bone used to restore the alveolar ridge. Specifically factors influencing (1) graft survival, (2) type, and (3) degree of bone resorption were evaluated. One hundred and thirteen maxillae and 27 mandibles were grafted. The surgical techniques used were 102 inlay, 27 onlay, and 11 veneer. Measurements were taken on pre-operative, post-operative, and follow-up radiographs. Data were processed by using three statistical methods: Kaplan–Meier algorithm, Cox regression, and curve estimation. As regards graft survival, Cox regression output showed a statistically significant effect only on surgical technique (P = 0.0312) and Kaplan–Meier algorithm demonstrated a worse outcome for veneer surgical technique (Log rank test = 0.0242). The Curve estimation demonstrated an inverse correlation between degree of bone resorption over time, with a progressive decrease. In conclusion FFB is a reliable material for alveolar bone restoration with a predicable average of resorption.

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Acknowledgments

This work was supported by FAR from the University of Ferrara (FC), Ferrara, Italy and from Regione Emilia Romagna, Programma di Ricerca Regione Universita’ 2007–2009 Area 1B: Patologia osteoarticolare: ricerca pre-clinica e applicazioni cliniche della medicina rigenerativa Unità Operativa n. 14.

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Correspondence to Francesco Carinci.

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Franco, M., Viscioni, A., Rigo, L. et al. Iliac crest fresh frozen homografts used in pre-prosthetic surgery: a retrospective study. Cell Tissue Bank 10, 227–233 (2009). https://doi.org/10.1007/s10561-008-9118-8

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  • DOI: https://doi.org/10.1007/s10561-008-9118-8

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