Abstract
Intraoral bone defects may be treated using autologous grafts, homologous grafts, heterologous grafts or synthetic products. Autologous bone is now considered the gold standard for bone grafting procedures. Homologous fresh frozen bone, provided by bone banks, is frequently utilized by orthopaedic surgeons because it is considered a safe material from immunological and viral points of view.In the cases reported here, homologous bone was used to repair some osseous defects without changing the surgical protocol utilized for autologous bone procedures. The main advantages of this strategy are low morbidity, shorter surgical times, more comfort and less risk of infection for the patient as well as the greater availability of bone.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Bauer TW, Musclher GF (2000) Bone graft materials. Clin Orthop 371:10–27
Becker W, Schenk R, Higuchi K, Lekholm U, Becker BE (1995) Variation in bone regeneration adjacent to implants augmented with barrier membranes alone or with demineralized freeze dried bone or autologous grafts: a study in dogs. Int J Oral Maxillofac Impl 10:143–154
Boyne PJ (1971) Transplantation, implantation and grafts. Dent Clin North Am 15:433–453
Burchardt H (1983) The biology of bone graft repair. Clin Orthop Rel Res 174:28–42
Carnes DI, Cochran DL, Melloning TJ (1999) Evaluation of two novel approaches for assessing the ability of DFDBA to induce new bone formation. J Periodontol 70:353–363
Cawood JI, Howell RA (1988) A classification of the edentulous jaw. Int J Oral Maxillofac Surg 17:232–236
Chiapasco M, Romeo E (2003) La riabilitazione implantoprotesica nei casi complessi. UTET, Milano
Di Stefano DA, Cazzaniga A (2003) Prelievi ossei intra ed extraorali. Masson, Milano
Elves MW, Pratt LM (1975) The pattern of new bone formation in isografts of bone. Acta Orthop Scand 46:549–560
Enneking WF (1962) Immunologic aspects of bone transplantation. South Med J 55:894–899
Frost DE, Fonseca RJ, Burkes EJ (1982) Healing of interpositional allogenic lyophilized bone grafts following total maxillary osteotomy. J Oral Maxillofac Surg 40:776–786
Isaksson S, Alberius P (1992) Comparison of regenerative capacity elicited by demineralized bone matrix of different embryologic origins. J Cranio Maxillofac Surg 20:73–80
Kubler N, Reuther J, Kircher T, Priessnitz B, Sebald W (1993) Osteoinductive, morphologic and biomechanical properties of autolyzed antigen extracted allogeneic human bone. J Oral Maxillofac Surg 51:1346–1357
Lekholm U, Zarb G (1985) Patient selection and preparation. In: Brånemark P-I, Zarb G, Albrektsson T (eds) Tissue-integrated prostheses: osteointegration in clinical dentistry. Quintessence, Chicago, pp 199–209
Marx RE (1994) Clinical application of bone biology to mandibular and maxillary reconstruction. Clin Plast Surg 3:377–392
Mizutani A, Fujita T, Watanabe S, Sakakida K, Okada Y (1990) Experiments on antigenicity and osteogenicity in allotransplanted cancellous bone. Int Orthop 14:243–248
Nishibori M, Betts NJ, Salama H, Listqarten MA (1994) Short term healing of autogenous and allogenic grafts after sinus augmentation: a report of two cases. J Periodontol 65:958–966
Okada Y, Sakakida K, Fujita T, Mizutabi A (1990) Experimental studies on half-joint transplantation. Antigenicity of fresh allografted articular cartilage and changes in the articular cartilage. Int Orthop 14:261–267
Perrott DH, Smith RA, Kaban LB (1992) The use of fresh frozen allogenic bone for maxillary and mandibular reconstruction. Int J Oral Maxillofac Surg 21:260–265
Pinholt EM, Haanaes HR, Donath K (1990) Alveolar ridge augmentation by osteoinductive materials in goats. Scand J Dent Res 100:361–365
Roth WK, Buhr S, Drosten C, Seifried E (2000) NAT and viral safety in blood transfusion. Vox Sang 78(suppl 2):257–259
Shasha N, Krywulak S, Backstein D, Pressman A, Gross AE (2003) Long-term follow-up of fresh tibial osteochondral allografts for failed tibial plateau fractures. J Bone Joint Surg Am 85(suppl 2):33–39
Stevenson S, Li XQ, Davy DT, Klein L, Goldberg VM (1997) Critical biological determinants of incorporation of non-vascularized cortical bone grafts. Quantification of a complex process and structure. J Bone Joint Surg Am 79:1–16
Tinti C, Parma-Benfenati S (2003) Clinical classification of bone defects concerning the placement of dental implants. Int J Period Res Dent 23:147–156
Wetzel AC, Stich H, Caffesse RG (1995) Bone apposition onto oral implant in the sinus area filled with different grafting materials. A histological study in beagle dogs. Clin Oral Impl Res 6:155–163
Whittaker JM, James RA, Lozada J, Cordova C, GaRey DJ (1989) Histological response and clinical evaluation of heterograft and allograft materials in the elevation of the maxillary sinus floor for the preparation of endosteal dental implant sites. J Oral Impl 2:141–144
Wood RM, Moore DL (1998) Grafting of the maxillary sinus with intraorally harvested autogenous bone prior to implant placement. Int J Oral Maxillofac Impl 3:209–214
Acknowledgments
The authors thank Prof. M. Spinelli of the Italian Diagnostic Centre and Dr. M. Marcer, Director of the Orthopaedic Department, Ospedale Civile Maggiore, Verona (Italy).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
D’Aloja, E., Santi, E., Aprili, G. et al. Fresh frozen homologous bone in oral surgery: case reports. Cell Tissue Banking 9, 41–46 (2008). https://doi.org/10.1007/s10561-007-9053-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10561-007-9053-0