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Iron Status Screening in Individuals with Heart Failure Before Initiating Sodium-Glucose Cotransporter 2 Inhibitor Therapy: Is It Necessary?

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References

  1. Packer M. SGLT2 inhibitors: role in protective reprogramming of cardiac nutrient transport and metabolism. Nature Reviews Cardiology. 2023;20(7):443–62.

    Article  CAS  PubMed  Google Scholar 

  2. Yang Z, Li T, Xian J, et al. SGLT2 inhibitor dapagliflozin attenuates cardiac fibrosis and inflammation by reverting the HIF-2α signaling pathway in arrhythmogenic cardiomyopathy. The FASEB Journal. 2022;36(7):e22410.

    Article  CAS  PubMed  Google Scholar 

  3. Mazer CD, Hare GM, Connelly PW, et al. Effect of empagliflozin on erythropoietin levels, iron stores, and red blood cell morphology in patients with type 2 diabetes mellitus and coronary artery disease. Circulation. 2020;141(8):704–7.

    Article  PubMed  Google Scholar 

  4. Packer M. Potential interactions when prescribing SGLT2 inhibitors and intravenous iron in combination in heart failure. JACC Heart Fail. 2023;11(1):106–14. https://doi.org/10.1016/j.jchf.2022.10.004.

    Article  PubMed  Google Scholar 

  5. McDowell LA, Kudaravalli P, Sticco KL. Iron Overload. 2022 Apr 28. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. 

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Conceptualization: An.C, A.C

Original draft-writing: An.C, A.C

Approval: An.C, A.C

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Correspondence to Aleksandar Cirovic.

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Cirovic, A., Cirovic, A. Iron Status Screening in Individuals with Heart Failure Before Initiating Sodium-Glucose Cotransporter 2 Inhibitor Therapy: Is It Necessary?. Cardiovasc Drugs Ther (2023). https://doi.org/10.1007/s10557-023-07498-1

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  • DOI: https://doi.org/10.1007/s10557-023-07498-1

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