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Left atrial strain associated with interatrial block in patients with ST-segment elevation myocardial infarction

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Abstract

Both interatrial block (IAB) and left atrium (LA) strain are associated with atrial arrhythmias in ST-segment elevation myocardial infarction (STEMI) patients, but the relationship between IAB and LA strain has not yet been reported. This study was to investigate the correlation between LA strain and IAB in STEMI patients. This is a single-center retrospective clinical observational study. The STEMI patients with primary percutaneous coronary intervention (pPCI) were enrolled, and all patients completed cardiac magnetic resonance (CMR). A standard 12-lead electrocardiogram (ECG) was recorded on the same day as CMR. IAB was measured by p duration on ECG at follow-up. 302 patients were enrolled, including 91 (30.1%) with IAB. The reservoir strain, conduit strain and booster strain were included in model 1, model 2 and model 3, respectively. In model 1, age (OR 1.025; 95%CI 1.003–1.047; p = 0.026), hypertension (OR 2.188; 95%CI 1.288–3.719; p = 0.004), and reservoir strain (OR 0.947; 95%CI 0.920–0.974; p < 0.001) were independent factors for IAB. In model 2, age (OR 1.031; 95%CI 1.009–1.053; p = 0.006), hypertension (OR 2.058; 95%CI 1.202–3.522; p = 0.008), RCA lesions (OR 1.797; 95%CI 1.036–3.113; p = 0.037), and conduit strain (OR 0.910; 95%CI 0.868–0.953; p < 0.001) were independent factors for IAB. In model 3, age (OR 1.022; 95%CI 1.001–1.045; p = 0.044), hypertension (OR 2.239; 95%CI 1.329–3.773; p = 0.002), and booster strain (OR 0.948; 95%CI 0.908–0.991; p = 0.019) were independent factors for IAB. With the lowest AIC and BIC values, model 2 was the best-fit model. LA strain associated with IAB in STEMI patients. The model including conduit strain was the best-fit one.

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Data availability

The datasets generated during and/or analyzed during the current study are available by request.

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  1. Lei Chen and Dongdong Zhang have contributed equally to this work.

Authors and Affiliations

  1. Department of Cardiology, The Affiliated Hospital of Xuzhou Medical University, 99#, Huaihai West Road, Xuzhou, 221002, China

    Lei Chen, Chuanyi Sang, Yixuan Wu, Yanfei Ren & Yuan Lu

  2. Department of Cardiology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, Shanghai, China

    Lei Chen

  3. Department of Cardiology, Taizhou People’s Hospital Affiliated to Nanjing Medical University, Taizhou, China

    Dongdong Zhang

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Contributions

LC and DZ performed this study and wrote the manuscript. CS and LC analyzed the CMR imaging. YW and YR were involved in data collection. YL directed the entire research work and corrected the articles. All authors read and approve the manuscript and agree to be accountable for all aspects of the research in ensuring that the accuracy or integrity of any part of the work is appropriately investigated and resolved.

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Correspondence to Yuan Lu.

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The study was reviewed by the Ethics Committee of the Affiliated Hospital of Xuzhou Medical University.

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Chen, L., Zhang, D., Sang, C. et al. Left atrial strain associated with interatrial block in patients with ST-segment elevation myocardial infarction. Int J Cardiovasc Imaging 40, 477–485 (2024). https://doi.org/10.1007/s10554-023-03011-9

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