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Normal reference values of cardiac chamber sizes and functional parameters in a beninese community population: the TAHES study

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Abstract

Reported ranges of normal values for echocardiographic measurements are mostly issued from studies performed in Caucasians. This study is a part of TAHES, a population-based prospective cohort study in Benin and aims to establish normal reference values for echocardiographic cardiac chambers dimensions and Doppler parameters in a Sub-Saharan African population. We included 486 healthy (non-diabetic, non-obese and normotensive) individuals (202 men and 284 women, age 37[30–47] years, BSA 1.58 (1.47–1.67) m2). End-diastolic interventricular septal wall thickness, left ventricular (LV) internal diameter, posterior wall thicknesses, and systolic LV internal diameter were respectively at 10[9–12], 45[43–49], 9[8–11], 29[26–34] mm for male and 9[7–10], 43[41–46], 8[7–], 29[27–32] mm for females. LV mass was significantly greater in males even after normalization for the body surface area (98[85–117] vs. 82[71–96] g/m2). Upper limits of BSA-indexed LV mass were 145 g/m2 for males and 124 g/m2 for females. The allometric exponent that described the LV mass-Height relationship were 2.5 in both sexes but 1.2 for males and 1.8 for females separately. E-wave velocity was 0.79 [0.65–0.90] cm/sec in males and 0.88 [0.78–0.99]cm/sec in females (p < 0.0001) but without significant gender differences in E/A ratio (limits: 0.75 and 2.1). The e′-wave velocity (lower limit = 8 cm/sec) decreased and E/e′ ratio (Upper limit = 9) increased with aging. Upper limit of BSA-indexed left atrium volume was 38 mL/m2 for both sexes. In conclusion, normal values from a general population in West Africa differ from those established in Caucasian populations with greater LV mass and wall thicknesses.

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Funding

This study was supported by the Conseil Régional de Nouvelle Aquitaine (Grant number non applicable).

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Authors and Affiliations

  1. Inserm U1094, IRD U270, Univ. Limoges, CHU Limoges, Limoges, 87042, France

    David Vandroux, Yessito Corine Houehanou, Julien Magne, Dismand Houinato, Pierre Marie Preux, Victor Aboyans & Philippe Lacroix

  2. EpiMaCT - Epidemiology of Chronic Diseases in Tropical Zone, Institute of Epidemiology and Tropical Neurology, OmegaHealth, Limoges, France

    David Vandroux, Yessito Corine Houehanou, Julien Magne, Dismand Houinato, Pierre Marie Preux, Victor Aboyans & Philippe Lacroix

  3. Cardio-surgical Intensive Care Unit, CHU Limoges, 2 Avenue Martin Luther King, Limoges, 87042, France

    David Vandroux

  4. Faculty of Health Sciences, Laboratory of Chronic and Neurologic Diseases Epidemiology, University of Abomey-Calavi, Cotonou, Bénin

    Yessito Corine Houehanou, Dominique Saka, Arnaud Sonou, Salmane Amidou & Dismand Houinato

  5. Cardiology Unit, CNHU Cotonou, Cotonou, Bénin

    Yessito Corine Houehanou, Dominique Saka & Arnaud Sonou

  6. Department of Cardiology, CHU Limoges, Limoges, France

    Julien Magne & Victor Aboyans

  7. Vascular Medicine Unit, CHU Limoges, Limoges, France

    Philippe Lacroix

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  1. David Vandroux
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  2. Yessito Corine Houehanou
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Contributions

David Vandroux: Formal Analysis, Investigation, Resources, DataCuration, Writing−Original Draft, Writing−Review &Editing. Victor Aboyans: Conceptualization, Methodology, Validation, Visualization, Supervision, Writing−Review &Editing, Project Administration, Funding Acquisition. Yessito Houehanou: Investigations, Resources, Data Curation. Dominique SAKA: Investigations, Resources, Data Curation. Arnaud SONOU: Investigations, Resources, Data Curation. Dismand HOUINATO: Conceptualization, Methodology, Validation, Resources, Funding Acquisition. Pierre-Marie Preux: Conceptualization, Project Administration, Funding Acquisition. Julien Magne: Formal Analysis, Resources, DataCuration, Supervision, Writing−Review &Editing. Philippe Lacroix: Conceptualization, Methodology, Formal Analysis, Writing−Review & Editing, Project Administration, Funding Acquisition.

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Correspondence to David Vandroux.

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Vandroux, D., Houehanou, Y.C., Magne, J. et al. Normal reference values of cardiac chamber sizes and functional parameters in a beninese community population: the TAHES study. Int J Cardiovasc Imaging 39, 1729–1739 (2023). https://doi.org/10.1007/s10554-023-02892-0

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