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Effect of percutaneous closure on atrium and appendage functions in patients with secundum atrial septal defects

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Abstract

Background

The study aimed to assess the impact of percutaneous transcatheter atrial septal defect (ASD) closure on atrium and atrial appandage functions among patients with ostium secundum ASDs.

Methods

A total of 101 patients (34,7% male, 65,3% female, 37,6 ± 12) with the diagnosis of ostium secundum type ASD underwent transthorasic (TTE) and transesophageal echocardiography (TEE) before and six months after percutaneous transcatheter ASD closure. Pulmonary venous flow and atrial appendage flow velocities were obtained from the TEE recordings. The offline evaluation of the global and segmental atrial appendage strains were evaluated with speckle tracking echocardiography (STE) via EchoPac 6,3 (GE Vingmed, Horten, Norway).

Results

Mean values of pulmonary artery pressure, right ventricular, left atrium, left ventricular end-diastolic and end-systolic diameters were significantly decreased 6 months after ASD closure. Statistically significant changes were documented in pulmonary venous and left atrial appendage flow velocities after ASD closure. Both left and right atrial appendage flow velocities and global strains of atrial appandages were improved after ASD closure. The mean left atrial appendage global strain value was − 11.45 ± 4.13% before the procedure, this value was − 16.82 ± 3.78% sixth months after the procedure (P < 0.001).The mean right atrial appendage global strain was − 13.31 ± 4.84% before the procedure and − 18.53 ± 4.69% sixth months after the procedure (P < 0.001).

Conclusion

Left and right atrial appendage flow velocities and global strains of left and right atrial appandage can be improved after transcatheter ASD closure. Percutaneous transcatheter closure of ASDs not only improves atrial and left ventricular dimensions but also have a positive impact on left and right atrial appandage functions.

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The authors declare that no funds, grants, or other support were received during the preparation of this manuscript.

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Authors and Affiliations

  1. Department of Cardiology, Bursa Acibadem Hospital, Bursa, Turkey

    Senol Coskun

  2. Department of Cardiology, Kocaeli University School of Medicine, Kocaeli, Turkey

    Kurban Ali Adina, Tayfun Sahin & Teoman Kilic

  3. Department of Cardiology, Bursa City Hospital, 16160 Nilufer, Bursa, Turkey

    Selma Kenar Tiryakioglu

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  1. Senol Coskun
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  2. Kurban Ali Adina
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  3. Selma Kenar Tiryakioglu
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  4. Tayfun Sahin
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  5. Teoman Kilic
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Contributions

S.C.: Substantial contributions to the conception and design or the acquisition, analysis, or interpretation of the data; K.A.A.: Substantial contributions to the conception and design or the acquisition, analysis, or interpretation of the data; S.K.T.: Substantial contributions to the drafting of the articles or critical revision for important intellectual content and final approval of the version to be published; T.S.: Substantial contributions to the conception and design or the acquisition, analysis, or interpretation of the data and substantial contributions to the drafting of the articles or critical revision for important intellectual content and final approval of the version to be published; T.K.: Substantial contributions to the conception and design or the acquisition, analysis, or interpretation of the data and substantial contributions to the drafting of the articles or critical revision for important intellectual content and final approval of the version to be published.

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Correspondence to Selma Kenar Tiryakioglu.

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The authors have no relevant financial or non-financial interests to disclose.

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This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of Kocaeli University.

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Coskun, S., Adina, K.A., Tiryakioglu, S.K. et al. Effect of percutaneous closure on atrium and appendage functions in patients with secundum atrial septal defects. Int J Cardiovasc Imaging 39, 1289–1297 (2023). https://doi.org/10.1007/s10554-023-02843-9

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  • DOI: https://doi.org/10.1007/s10554-023-02843-9

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