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Ventriculo-arterial coupling in patients with stable ischemic heart disease undergoing percutaneous coronary intervention

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Abstract

To investigate ventriculo-arterial coupling (VAC) and its components (Ea, Ees) in patients with stable ischemic heart disease and changes following percutaneous coronary intervention (PCI). 129 patients with stable ischemic heart disease (SIHD) undergoing PCI (study group) and 40 individuals without IHD (control group) were enrolled. VAC was calculated using echocardiography method at baseline and 1, 3, and 6 months after PCI. A linear mixed-effects models with restricted maximum likelihood were used to assess the impact of PCI on Ea, Ees, VAC over 6-month follow-up. Mean age of the SIHD group was 67.8 ± 8.1 (years), and predominantly men (73.6%). In the SIHD group, baseline median Ea, Ees and VAC were 2.52 (IQR 1.89–3.28) (mmHg/ml), 3.87 (IQR 2.90–4.95) (mmHg/ml), and 0.64 (IQR 0.54–0.79), respectively. Patients with SIHD had significantly lower Ees and higher VAC when compared to the control group (p < 0.05). Ees (p = 0.01) and VAC (p < 0.001) were significantly improved over 6 month follow-up after PCI. Notably, the degree of VAC improvement appears to be related to stented artery (Table 3). VAC obtained from echocardiographic methodology demonstrated a significant increase in patients with SIHD at baseline. This observation may represent a plausible mechanism for the benefit of PCI in SIHD. Hence, VAC may be a feasible parameter in the assessment of patients with SIHD.

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The authors received no financial support for this work.

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  1. Hung Tran Duc and Ha Pham Vu Thu have contributed equally in the manuscript.

Authors and Affiliations

  1. Department of Cardiology, Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam

    Hung Tran Duc, Ha Pham Vu Thu, Oanh Nguyen Oanh & Thuc Luong Cong

  2. The Heart and Vascular Center and The Lindner Research Center, The Christ Hospital Health Network, Cincinnati, OH, USA

    Vien T. Truong, Tam N. M. Ngo, Wojciech Mazur & Eugene S. Chung

  3. Military Hospital 103, Vietnam Military Medical University, Hanoi, Vietnam

    Tien Tran Viet

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  1. Hung Tran Duc
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  2. Ha Pham Vu Thu
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These authors take responsibility for all aspects of the reliability and freedom from bias of the data presented and their discussed interpretation.

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Correspondence to Thuc Luong Cong.

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The study was approved by the hospital's Institutional Review Board.

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Duc, H.T., Thu, H.P.V., Truong, V.T. et al. Ventriculo-arterial coupling in patients with stable ischemic heart disease undergoing percutaneous coronary intervention. Int J Cardiovasc Imaging 38, 571–577 (2022). https://doi.org/10.1007/s10554-021-02437-3

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  • DOI: https://doi.org/10.1007/s10554-021-02437-3

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