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Changes in mitral valve geometry after percutaneous valve repair with the MitraClip® System

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Abstract

The aim of our study was to assess the anatomical changes of the mitral valve apparatus after percutaneous repair with the MitraClip® system. We included consecutive patients who underwent MitraClip® implantation in our center. Patients were assessed by 2- and 3-dimensional transesophageal echocardiography, acquired before and immediately after MitraClip® implantation. Off-line images analysis was performed to assess mitral annular diameters (antero-posterior and inter-commisural), area and circumference. Mitral tenting distance, area and volume were evaluated for functional mitral regurgitation. Patients had a 2-dimensional transthoracic echocardiography at follow-up (8 months). 38 patients with successful results (residual mitral regurgitation grade ≤ II) were included. The anteroposterior annulus diameter (ADP) decreased (from 35 ± 5 to 28 ± 5 mm, p < 0.001) with smaller decreases in the annular area and circumference and in the inter-commissural diameter. Annular ellipticity improved. The reduction in APD and tenting distance was sustained at follow-up. Successful percutaneous mitral valve repair with the MitraClip® system induces a stable change in mitral valve geometry mainly at the ADP, suggesting a significant annuloplasty that contributes to the reduction of mitral regurgitation.

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Abbreviations

MR:

Mitral regurgitation

LV:

Left ventricle

TEE:

Transesophageal echocardiographic

3DQ:

Three dimensional quantification

MVN:

Mitral Valve Navigation

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Authors and Affiliations

  1. Cardiovascular Institute, Hospital Clínic Barcelona, Universitat de Barcelona, Villarroel 170, 08036, Barcelona, Spain

    Livia Trasca, Laura Sanchis, Ander Regueiro, Xavier Freixa & Marta Sitges

  2. CERCA Programme/Generalitat de Catalunya, Institut D’Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain

    Livia Trasca, Laura Sanchis, Ander Regueiro, Xavier Freixa & Marta Sitges

  3. Centro de Investigación Biomédica en Red Enfermedades Cardiovasculares (CIBERCV), Instituto de Salud Carlos III (CB16/11/00354), Madrid, Spain

    Livia Trasca & Marta Sitges

  4. Carol Davila, University of Medicine and Pharmacy, Bucharest, Romania

    Dragos Vinereanu

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  1. Livia Trasca
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  2. Laura Sanchis
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Correspondence to Laura Sanchis.

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Trasca, L., Sanchis, L., Regueiro, A. et al. Changes in mitral valve geometry after percutaneous valve repair with the MitraClip® System. Int J Cardiovasc Imaging 37, 1577–1585 (2021). https://doi.org/10.1007/s10554-020-02137-4

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  • DOI: https://doi.org/10.1007/s10554-020-02137-4

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