Skip to main content
Log in

Letter to the editor: is it time for imaging to level with pathology?

  • Review Paper
  • Published:
The International Journal of Cardiovascular Imaging Aims and scope Submit manuscript

Abstract

CMR provides pathology-like insights of myocardial abnormality, such as hyperemia, edema, necrosis and fibrosis, which is in-vivo, non-invasive and real-time. Hence, it is most likely to become one alternative tool for mimicking pathology, so-called pathologicalized imaging due to its extraordinary tissue characteristics. This article aims to call for a wider clinical application of CMR with more attention on its tissue characterization value.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Bax JJ, Di Carli M, Narula J, Delgado V (2019) Multimodality imaging in ischaemic heart failure. Lancet 393(10175):1056–1070

    Article  Google Scholar 

  2. Gulati A, Jabbour A, Ismail TF et al (2013) Association of fibrosis with mortality and sudden cardiac death in patients with nonischemic dilated cardiomyopathy. JAMA 309(9):896–908

    Article  CAS  Google Scholar 

  3. Zhou D, Xu J, Zhao S et al (2020) CMR publications from China of the last more than 30 years. Int J Cardiovasc Imaging. https://doi.org/10.1007/s10554-020-01873-x

    Article  PubMed  PubMed Central  Google Scholar 

  4. Kim RJ, Fieno DS, Parrish TB et al (1999) Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function. Circulation 100(19):1992–2002

    Article  CAS  Google Scholar 

  5. Chan RH, Maron BJ, Olivotto I et al (2014) Prognostic value of quantitative contrast-enhanced cardiovascular magnetic resonance for the evaluation of sudden death risk in patients with hypertrophic cardiomyopathy. Circulation 130(6):484–495

    Article  Google Scholar 

  6. Moravsky G, Ofek E, Rakowski H et al (2013) Myocardial fibrosis in hypertrophic cardiomyopathy: accurate reflection of histopathological findings by CMR. JACC Cardiovasc Imaging 6(5):587–596

    Article  Google Scholar 

  7. Nakamori S, Dohi K, Ishida M et al (2018) Native T1 mapping and extracellular volume mapping for the assessment of diffuse myocardial fibrosis in dilated cardiomyopathy. JACC Cardiovasc Imaging 11(1):48–59

    Article  Google Scholar 

  8. Xu J, Zhuang B, Sirajuddin A et al (2020) MRI T1 mapping in hypertrophic cardiomyopathy: evaluation in patients without late gadolinium enhancement and hemodynamic obstruction. Radiology 294(2):275–286

    Article  Google Scholar 

  9. Carrick D, Haig C, Ahmed N et al (2016) Myocardial hemorrhage after acute reperfused ST-segment-elevation myocardial infarction: relation to microvascular obstruction and prognostic significance. Circ Cardiovasc Imaging 9(1):e004148

    Article  Google Scholar 

  10. Garcia J, Barker AJ, Markl M (2019) The role of imaging of flow patterns by 4D flow MRI in aortic stenosis. JACC Cardiovasc Imaging 12(2):252–266

    Article  PubMed  Google Scholar 

  11. Leng S, Ge H, He J et al (2020) Long-term prognostic value of cardiac MRI left atrial strain in ST-segment elevation myocardial infarction. Radiology. https://doi.org/10.1148/radiol.2020200176

    Article  PubMed  PubMed Central  Google Scholar 

  12. Ferreira VM, Schulz-Menger J, Holmvang G et al (2018) Cardiovascular magnetic resonance in nonischemic myocardial inflammation: expert recommendations. J Am Coll Cardiol 72(24):3158–3176

    Article  Google Scholar 

Download references

Funding

The study was supported by grant No. 81930044 and No. 81620108015 from the key projects of National Natural Science Foundation of China.

Author information

Authors and Affiliations

Authors

Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by SZ. The first draft of the manuscript was written by SZ and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Shihua Zhao.

Ethics declarations

Conflict of interest

No potential conflicts of interest with respect to the research, authorship, and/or publication of this articles.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Zhao, S. Letter to the editor: is it time for imaging to level with pathology?. Int J Cardiovasc Imaging 36, 2249–2250 (2020). https://doi.org/10.1007/s10554-020-01936-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10554-020-01936-z

Keywords

Navigation