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Comparison of conventional and cadmium–zinc–telluride single-photon emission computed tomography for analysis of thallium-201 myocardial perfusion imaging: an exploratory study in normal databases for different ethnicities

The International Journal of Cardiovascular Imaging volume 33, pages 2057–2066 (2017)Cite this article

Abstract

The aim of this study was to clarify the differences in thallium-201–chloride (thallium-201) myocardial perfusion imaging (MPI) scans evaluated by conventional anger-type single-photon emission computed tomography (conventional SPECT) versus cadmium–zinc–telluride SPECT (CZT SPECT) imaging in normal databases for different ethnic groups. MPI scans from 81 consecutive Japanese patients were examined using conventional SPECT and CZT SPECT and analyzed with the pre-installed quantitative perfusion SPECT (QPS) software. We compared the summed stress score (SSS), summed rest score (SRS), and summed difference score (SDS) for the two SPECT devices. For a normal MPI reference, we usually use Japanese databases for MPI created by the Japanese Society of Nuclear Medicine, which can be used with conventional SPECT but not with CZT SPECT. In this study, we used new Japanese normal databases constructed in our institution to compare conventional and CZT SPECT. Compared with conventional SPECT, CZT SPECT showed lower SSS (p < 0.001), SRS (p = 0.001), and SDS (p = 0.189) using the pre-installed SPECT database. In contrast, CZT SPECT showed no significant difference from conventional SPECT in QPS analysis using the normal databases from our institution. Myocardial perfusion analyses by CZT SPECT should be evaluated using normal databases based on the ethnic group being evaluated.

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Acknowledgements

The authors thank all their coworkers, including the radiological technologists and cardiologists, at Hyogo Brain and Heart Center at Himeji, Himeji.

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Affiliations

  1. Department of Radiology, Hyogo Cancer Center, 13-70 Kitaoji, Akashi, Hyogo, 673-8558, Japan

    Masaru Ishihara

  2. Department of Quantum Medical Technology, Graduate School of Medical Sciences, Kanazawa University, 5-11-80 Kodatsuno, Kanazawa, Ishikawa, 920-0942, Japan

    Masaru Ishihara, Masahisa Onoguchi & Takayuki Shibutani

  3. Department of Cardiology, Hyogo Brain and Heart Center at Himeji, 520 Saisho-ko, Himeji, Hyogo, 670-0981, Japan

    Yasuyo Taniguchi

Authors
  1. Masaru Ishihara
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  2. Masahisa Onoguchi
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  3. Yasuyo Taniguchi
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  4. Takayuki Shibutani
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Correspondence to Masahisa Onoguchi.

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Ishihara, M., Onoguchi, M., Taniguchi, Y. et al. Comparison of conventional and cadmium–zinc–telluride single-photon emission computed tomography for analysis of thallium-201 myocardial perfusion imaging: an exploratory study in normal databases for different ethnicities. Int J Cardiovasc Imaging 33, 2057–2066 (2017). https://doi.org/10.1007/s10554-017-1205-0

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  • DOI: https://doi.org/10.1007/s10554-017-1205-0

Keywords

  • Solid-state dedicated cardiac gamma camera
  • Conventional anger-type gamma camera
  • Single-photon emission computed tomography
  • Myocardial perfusion imaging
  • Thallium-201