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Using DynaCT for the assessment of ilio-femoral arterial calibre, calcification and tortuosity index in patients selected for trans-catheter aortic valve replacement


Adequate vascular access for femoral trans-catheter aortic valve replacement is fundamental to the success of the procedure. Assessment of vascular calibre, tortuosity and calcification is performed by angiography and multi-slice computed tomography (MSCT). Can DynaCT provide the same information as MSCT? 15 Patients underwent MSCT, angiography and DynaCT. Vessel diameter measurements were taken in three positions of the left and right ilio-femoral arteries. Tortuosity was assessed using an index of the direct distance and the distance taken by the artery between two points. Calcification was assessed in MSCT and DynaCT using a simple scoring system. Concordance correlation coefficient of arterial calibre between angiography and MSCT was 0.96 (95 % CI 0.94–0.97). DynaCT and angiography was 0.94 (95 % CI 0.91–0.96) and Dyna CT and MSCT, 0.95 (95 % CI 0.92–0.97). Bland–Altman tests demonstrate a mean difference between the angiogram and the MSCT of 0.06 mm (+0.97, −1.42), angiogram and DynaCT, 0.13 mm, (+1.00, −0.87), DynaCT and MSCT, 0.2 mm, (+1.15, −0.76). Tortuosity comparisons gave a median tortuosity index for MSCT 1.29 and DynaCT 1.23 (p = 0.472). Calcification comparisons of MSCT and DynaCT using correlation coefficients demonstrate a correlation of 0.245 (p = 0.378). Effective radiation doses were: DynaCT; 3.63 ± 0.65 mSv and angiography; 0.57 ± 0.72 mSv, MSCT; 7.15 ± 2.58 mSv. DynaCT is equal to MSCT and angiography in assessing femoral artery calibre. Like MSCT, it can assess tortuosity and can produce 3D images but is inferior in the assessment of calcification.

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JinLin Fu (MBBS PHD) for his work in providing statistical analysis for this paper.

Conflict of interest

The Prince Charles Hospital is involved in a research collaboration with Siemens Healthcare. Dr. Darren Walters is a consultant for Siemens, Medtronic Inc., a Proctor for Edwards Lifesciences and principal investigator for SOURCE ANZ registry. There are no other stock ownership, or other equity interests or patent-licensing arrangements within the article.

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Correspondence to James A. Crowhurst.

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Crowhurst, J.A., Campbell, D., Raffel, O.C. et al. Using DynaCT for the assessment of ilio-femoral arterial calibre, calcification and tortuosity index in patients selected for trans-catheter aortic valve replacement. Int J Cardiovasc Imaging 29, 1537–1545 (2013).

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