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Comparison of global left ventricular function using 20 phases with 10-phase reconstructions in multidetector-row computed tomography

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Abstract

To compare the measurement of global left-ventricular (LV) function parameters of 64-slice multidetector-row computed tomography (MDCT) between 20- and 10-reconstruction phases. Fifty five patients with suspected or known coronary artery disease underwent 64-slice MDCT. LV end-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) were measured from MDCT data sets using threshold-based volume segmentation and reconstruction at every 5% (20 phases) and 10% (10 phases) step through the R-R interval. These global functional parameters were compared to those obtained via two-dimensional transthoracic echocardiography (2D-TTE), considering the reference standard. The required time for CT data analysis was checked. Agreement for parameters of LV global function was determined using Pearson’s correlation coefficient (r) and Bland–Altman analysis. LV volumes (EDV−5% 87.5 ± 17.1 ml, EDV−10% 87.7 ± 16.3 ml; ESV−5% 32.4 ± 10.6 ml, ESV−10% 31.9 ± 9.9 ml; SV−5% 55.1 ± 10.5 ml, SV−10% 55.8 ± 9.9 ml; mean ± SD) and EF (EF−5% 63.4 ± 6.2%, EF−10% 63.9 ± 5.8%) did not differ significantly between the 20- and 10 phase reconstructions, and evidenced good to excellent correlation (r = 0.786–0.896, all P < 0.001) with the 2D-TTE results. The mean required time for CT data analysis in the 20- and 10 phase reconstructions were 15.5 ± 4.0 and 7.3 ± 2.5 min. Within MDCT, using 10-phase image reconstruction is sufficient to evaluate LV volumes and EF, and is also more time-effective than 20-phase reconstruction.

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Abbreviations

ECG:

Electrocardiography

HR:

Heart rate

LV:

Left ventricle

LVEDV:

Left ventricular end-diastolic volume

LVEF:

Left ventricular ejection fraction

LVESV:

Left ventricular end-systolic volume

LVSV:

Left ventricular stroke volume

MDCT:

Multidetector-row computed tomography

MRI:

Magnetic resonance imaging

2D:

Two-dimensional

2D-TTE:

Two-dimensional transthoracic echocardiography

3D:

Three-dimensional

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Acknowledgments

This work was supported by Chungnam National University Hospital Research Fund 2010, Republic of Korea. The authors would like to thank the Chungnam National University Hospital.

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Authors and Affiliations

  1. Department of Radiology, Chungnam National University Hospital, Chungnam National University School of Medicine, 33 Munhwa-ro, Jung-gu, Daejeon, 301-721, Korea

    Yeon-jee Ko, Song Soo Kim & Woon-Ju Park

  2. Division of Cardiology, Departments of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea

    Jin-Ok Jeong

  3. Departments of Radiology, Konkuk University Hospital, Konkuk University School of Medicine, Seoul, Korea

    Sung Min Ko

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  1. Yeon-jee Ko
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  2. Song Soo Kim
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Correspondence to Song Soo Kim.

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Ko, Yj., Kim, S.S., Park, WJ. et al. Comparison of global left ventricular function using 20 phases with 10-phase reconstructions in multidetector-row computed tomography. Int J Cardiovasc Imaging 28, 603–611 (2012). https://doi.org/10.1007/s10554-011-9828-z

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  • DOI: https://doi.org/10.1007/s10554-011-9828-z

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