Abstract
Objective: The objective of the study was to estimate the capacity of pressure volume (PV) loop analysis to assess right ventricular (RV) function after Fallot (TOF) repair.Patients: Fifty six patients were examined after TOF repair. PV loops were constructed from RV angiocardiography and simultaneous pressure measurement. Patients were divided in three groups according to RV size and pressure (Group I: normal RV size and pressure; group II: enlarged RV, near normal pressure; group III: normal RV size, elevated pressure).Main outcome measures: Systolic stroke work corrected for body surface area (W/BSA) and for RV enddiastolic volume (W/EDV), peak RV filling (PFR) and emptying rates (PER) corrected for RV stroke volume, cycle efficiency (CE), RV ejection fraction (RVEF).Results: W/BSA was significantly higher in group II than in group I (0.19 ± 0.05 vs. 0.11 ± 0.04 J/m2, p < 0.001) and was similar between groups II and III (0.19 ± 0.05 vs. 0.17 ± 0.05 J/m2 ; NS). W/EDV was similar in groups I and II (12.4 ± 5.4 vs. 12.4 ± 2.9 mmHg; NS). CE was smallest in group II. The difference was significant between groups II and III (0.62 ± 0.08 vs. 0.73 ± 0.09; p < 0.05). RVEF was negatively correlated to RV end systolic volume (RVESV) in the patients of groups I and II (r = −0.32, p < 0.05). A similar correlation was found between PFR and RVESV (r = −0.28, p < 0.05).Conclusions: Analysis of a single PV loop allows quantification of RV load after TOF repair. W/BSA is increased to the same extent under volume and pressure load. The lack of decrease in W/EDV in patients with enlarged RV indicates that RV is capable to perform adequate work in a wide range. RVESV is a useful measure for estimating RV function after TOF repair depicting parameters of systolic and diastolic RV function.
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FA Pigula PN Khalil JE Mayer PJ del Nido RA Jonas (1999) ArticleTitleRepair of Tetralogy of Fallot in neonates and young infants Circulation 100 IssueID19 Suppl II157–61 Occurrence Handle10567296
AN Redington PJ Oldershaw EA Shinebourne ML Rigby (1988) ArticleTitleA new technique for the assessment of pulmonary regurgitation and its application to the assessment of right ventricular function before and after repair of Tetralogy of Fallot Br Heart J 60 IssueID1 57–65 Occurrence Handle3408618
PY Marie F Marcon F Brunotte et al. (1992) ArticleTitleRight ventricular overload and induced sustained ventricular tachycardia in operatively “repaired” Tetralogy of Fallot Am J Cardiol 69 IssueID8 785–789 Occurrence Handle10.1016/0002-9149(92)90506-T Occurrence Handle1546654
A Uebing G Fischer M Bethge et al. (2002) ArticleTitleInfluence of the pulmonary annulus diameter on pulmonary regurgitation and right ventricular pressure load after repair of tetralogy of Fallot Heart 88 IssueID5 510–514 Occurrence Handle10.1136/heart.88.5.510 Occurrence Handle12381646
WA Helbing RA Niezen S Le Cessie RJ Geest Particlevan der J Ottenkamp A Roos Particlede (1996) ArticleTitleRight ventricular diastolic function in children with pulmonary regurgitation after repair of tetralogy of Fallot: volumetric evaluation by magnetic resonance velocity mapping J Am Coll Cardiol 28 IssueID7 1827–1835 Occurrence Handle10.1016/S0735-1097(96)00387-7 Occurrence Handle8962573
DG Onnasch FK Schmiel K Moldenhauer HH Kramer (2002) ArticleTitleBiplane angiographic volumetry of the right and left heart ventricle with optimal image pairing Biomed Tech (Berl) 47 IssueIDSuppl 1 Pt 2 622–625
GPM Prause DGW Onnasch (1996) ArticleTitleBinary reconstruction of heart chambers from biplane angiographic image sequences IEEE Trans Med Imaging 15 IssueID4 532–546 Occurrence Handle10.1109/42.511756
PE Lange D Onnasch FL Farr PH Heintzen (1978) ArticleTitleAngiocardiographic right ventricular volume determination. Accuracy, as determined from human casts, and clinical application Eur J Cardiol 8 IssueID4–5 477–501 Occurrence Handle720367
PE Lange DG Onnasch GH Schaupp C Zill PH Heintzen (1982) ArticleTitleSize and function of the human left and right ventricles during growth. Normative angiographic data Pediatr Cardiol 3 IssueID3 205–211 Occurrence Handle7155958
AN Redington HH Gray ME Hodson ML Rigby PJ Oldershaw (1988) ArticleTitleCharacterisation of the normal right ventricular pressure-volume relation by biplane angiography and simultaneous micromanometer pressure measurements Br Heart J 59 IssueID1 23–30 Occurrence Handle3342146
WA Helbing A. Roos Particlede (2000) ArticleTitleClinical applications of cardiac magnetic resonance imaging after repair of tetralogy of Fallot Pediatr Cardiol 21 IssueID1 70–79 Occurrence Handle10.1007/s002469910009 Occurrence Handle10672616
H Takaoka M Takeuchi M Odake et al. (1993) ArticleTitleComparison of hemodynamic determinants for myocardial oxygen consumption under different contractile states in human ventricle Circulation 87 IssueID1 59–69 Occurrence Handle8419025
MA Gatzoulis S Balaji SA Webber et al. (2000) ArticleTitleRisk factors for arrhythmia and sudden cardiac death late after repair of tetralogy of Fallot: a multicentre study Lancet 356 IssueID9234 975–981 Occurrence Handle10.1016/S0140-6736(00)02714-8 Occurrence Handle11041398
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Uebing, A., Fischer, G., Schmiel, F. et al. Angiocardiographic Pressure Volume Loops in the Analysis of Right Ventricular Function after Repair of Tetralogy of Fallot. Int J Cardiovasc Imaging 21, 469–480 (2005). https://doi.org/10.1007/s10554-005-2102-5
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DOI: https://doi.org/10.1007/s10554-005-2102-5