Abstract
Metastatic cardiac myxoid liposarcoma is rare. We present the case of a 56-year-old woman who was admitted for angina and syncope, and in whom a mobile intracardiac mass obstructing the left ventricular outflow tract and protruding into the aortic root during systole was detected by transesophageal echocardiography (TEE). She reported an antecedent of the complete excision of a myxoid liposarcoma of the thigh 12 years before. A surgical resection procedure was performed through an excision of the anterior wall of the left ventricle. The histopathological analysis of the specimens obtained during surgery revealed a low-grade malignancy myxoid liposarcoma, similar to the one resected in the thigh 12 years before. The present case is the first one to report syncope due to left ventricular outflow tract as a cause for admission. TEE was able to visualize the metastatic tumor to the heart, accurately localize its position and allow for prompt surgical treatment that produced relief of the symptoms.
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References
L Suárez T. Cianciulli (1997) Tumores Cardíacos CA Bertolasi C Barrero G Gimeno G Liniado V Mauro (Eds) Cardiología 2000 EditionNumber1 Editorial Médica Panamericana, Buenos Aires 790–819
G Pinelli A Trihn JP Carteaux et al. (1996) ArticleTitlePrimary liposarcoma of the left ventricle. A propos of a case and review of the literature Arch Mal Coeur Vaiss 89 257–260 Occurrence Handle8678759
F Paraf P Bruneval A Balaton et al. (1990) ArticleTitlePrimary liposarcoma of the heart Am J Cardiovasc Pathol 3 175–180 Occurrence Handle2264989
EC Tong S Rubenfeld (1968) ArticleTitleCardiac metastasis from myxoid liposarcoma emphasizing its radiosensitivity Am J Roentgenol Radium Ther Nucl Med 103 792–799 Occurrence Handle5692417
JD Godwin L Axel JR Adams NB Schiller PC Simpson SuffixJr EW Gertz (1981) ArticleTitleComputed tomography: a new method for diagnosing tumor of the heart Circulation 63 448–451 Occurrence Handle7449067
C Mavroudis LW Way M Lipton EW Gertz RJ Ellis (1981) ArticleTitleDiagnosis and operative treatment of intracavitary liposarcoma of the right ventricle J Thorac Cardiovasc Surg 81 137–140 Occurrence Handle7453216
TS Ravikumar GP Topulos RW Anderson TB Grage (1983) ArticleTitleSurgical resection for isolated cardiac metastases Arch Surg 118 117–120 Occurrence Handle6848063
RA Pizzarello SM Goldberg MA Goldman et al. (1985) ArticleTitleTumor of the heart diagnosed by magnetic resonance imaging J Am Coll Cardiol 5 989–991 Occurrence Handle3973303
JL Lagrange P Despins M Spielman et al. (1986) ArticleTitleCardiac metastases. Case report on an isolated cardiac metastasis of a myxoid liposarcoma Cancer 58 2333–2337
P Bartels WG O’Callaghan R Peyton G Sethi T Maley (1988) ArticleTitleMetastatic liposarcoma of the right ventricle with outflow tract obstruction: restrictive pathophysiology predicts poor surgical outcome Am Heart J 115 696–698 Occurrence Handle10.1016/0002-8703(88)90828-9 Occurrence Handle3344669
JP Ozoux C Berton L de Calan L Guillou P Cosnay (1988) ArticleTitleCardiac metastasis from a myxoid liposarcoma J Thorac Cardiovasc Surg 96 668–669 Occurrence Handle3172814
SS Schrem SB Colvin JC Weinreb E Glassman I Kronzon (1990) ArticleTitleMetastatic cardiac liposarcoma: diagnosis by transesophageal echocardiography and magnetic resonance imaging J Am Soc Echocardiogr 3 149–153. Occurrence Handle2185795
F Maloisel P Dufour T Drawin et al. (1991) ArticleTitleEmbolization of the foramen ovale in metastatic course of abdominal liposarcoma Ann Cardiol Angeiol 40 81–84
JM Langlard M Lefevre M Fiche JC Chevallier O Godin JB Bouhour (1992) ArticleTitleRight atrioventricular metastasis of myxoid liposarcoma. Prolonged course after repeated surgery and chemotherapy Arch Mal Coeur Vaiss 85 1353–1356. Occurrence Handle1290400
M Oshima T Kondo Y Uno (1993) ArticleTitleMetastatic cardiac liposarcoma diagnosed by thallium-201 myocardial single photon emission computed tomography Clin Nucl Med 18 801–803 Occurrence Handle8403732
MZ Papa A Shinfeld E Klein F Greif G Ben-Ari (1994) ArticleTitleCardiac metastasis of liposarcoma J Surg Oncol 55 132–134 Occurrence Handle8121186
U Wilhelmi F Fellner N Friedel H Wieseler (1997) ArticleTitleMyxoid liposarcoma with pericardial metastasis Rontgenpraxis 50 119–121 Occurrence Handle9297255
K Gacem L Vachon T Benard C Delaire JM Bouvier (2000) ArticleTitleRight atrioventricular metastasis of a myxoid liposarcoma Case report and al review of the literature Arch Mal Coeur Vaiss 93 1155–1158 Occurrence Handle11055008
C Ng J Stebbing I Judson (2001) ArticleTitleCardiac metastasis from a myxoid liposarcoma Clin Oncol (R Coll Radiol) 13 384–385
DS Lee M Barnard MR Freeman SJ Hutchison AF Graham B Chiu (2002) ArticleTitleCardiac encasement by metastatic myxoid liposarcoma Cardiovasc Pathol 11 322–325 Occurrence Handle10.1016/S1054-8807(02)00131-X Occurrence Handle12459432
DE Hallahan NJ Vogelzang KM Borow DG Bostwick MA Simon (1986) ArticleTitleCardiac metastases from soft-tissue sarcomas J Clin Oncol 4 1662–1669 Occurrence Handle3772419
MC Murphy MS Sweeney JB Putnam SuffixJr et al. (1990) ArticleTitleSurgical treatment of cardiac tumors: a 25-year experience Ann Thorac Surg 49 612–617 Occurrence Handle2322057
A Llombart-Cussac X Pivot G Contesso et al. (1998) ArticleTitleAdjuvant chemotherapy for primary cardiac sarcomas: the IGR experience Br J Cancer 78 1624–1628 Occurrence Handle9862574
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Fairman, E.B., Mauro, V.M., Cianciulli, T.F. et al. Liposarcoma Causing Left Ventricular Outflow Tract Obstruction and Syncope: a Case Report and Review of the Literature. Int J Cardiovasc Imaging 21, 513–518 (2005). https://doi.org/10.1007/s10554-005-0653-0
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DOI: https://doi.org/10.1007/s10554-005-0653-0