Africa’s oesophageal cancer corridor: Do hot beverages contribute?

Abstract

Purpose

Hot beverage consumption has been linked to oesophageal squamous cell cancer (EC), but its contribution to the poorly understood East African EC corridor is not known.

Methods

In a cross-sectional study of general-population residents in Kilimanjaro, North Tanzania, tea drinking temperatures and times were measured. Using linear regression models, we compared drinking temperatures to those in previous studies, by socio-demographic factors and tea type (“milky tea” which can be 50 % or more milk and water boiled together vs “black tea” which has no milk).

Results

Participants started drinking at a mean of 70.6 °C (standard deviation 3.9, n = 188), which exceeds that in all previous studies (p ≤ 0.01 for each). Tea type, gender and age were associated with drinking temperatures. After mutual adjustment for each other, milky tea drinkers drank their tea 1.9 °C (95 % confidence interval: 0.9, 2.9) hotter than drinkers of black tea, largely because black tea cooled twice as fast as milky tea. Men commenced drinking tea 0.9 °C (−0.2, 2.1) hotter than women did and finished their cups 30 (−9, 69) seconds faster. 70 % and 39 % of milky and black tea drinkers, respectively, reported a history of tongue burning.

Conclusions

Hot tea consumption, especially milky tea, may be an important and modifiable risk factor for EC in Tanzania. The contribution of this habit to EC risk needs to be evaluated in this setting, jointly with that of the many risk factors acting synergistically in this multi-factorial disease.

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Acknowledgments

We would like to thank the village elders and members of the Machame community for their participation in this study and to the fieldworkers Mr Timothy Ngowi and Mr Leons. We thank the KCRI data management and data entry team for their assistance in this work. This study was funded by the International Agency for Research on Cancer (IARC) and was jointly conducted with the Kilimanjaro Clinical Research Institute (KCRI), an Institute of Kilimanjaro Christian Medical Centre (KCMC). Dr Oresto Munishi’s work on oesophageal cancer was supported by the 2012 UICC-IARC Development Fellowship; he is also partially supported by a HIV Associated Malignancies Training Program (HAMTRP) GRANT No. D43CA153722. During fieldwork, an MD4 medical student funded by the Medical Education Partnership Initiative HRSA grant T84-HA21123—Mentored Research Training Program (MEPI MRTP) of KCMC was mentored.

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Correspondence to Valerie McCormack.

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Munishi, M.O., Hanisch, R., Mapunda, O. et al. Africa’s oesophageal cancer corridor: Do hot beverages contribute?. Cancer Causes Control 26, 1477–1486 (2015). https://doi.org/10.1007/s10552-015-0646-9

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Keywords

  • Oesophageal cancer
  • Tanzania
  • Hot beverages
  • Tea