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Variations in breast cancer incidence per decade of life (Goiânia, GO, Brazil): 16-year analysis

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Abstract

Objective

To analyze the variation in breast cancer incidence, with stratification into ten-year age groups, 17 years after the nuclear accident in Goiânia.

Methods

Between 1988 and 2003, 3312 new cases were recorded. The crude and standardized incidence rates were calculated. ANOVA was used to obtain the coefficient of determination (R2) for the incidence over the course of the years, and p-values were obtained both by linear and by polynomial regression.

Results

The increases in crude and standardized incidence were statistically significant in all age groups, except for women between 20 and 29 years old. For the age group from 30 to 49 years, the increase in incidence was around 100% (p = 0.001), and from 50 to 59 years, 277% (p < 0.001). More modest increases of around 50% were observed in the age groups from 60 to 79 years (p = 0.013). For the women aged 80 years and over, the increase was 272% (p = 0.015).

Conclusions

There were significant increases in the crude and standardized incidence rates for breast cancer in the city of Goiânia. The women in the age group from 50 to 59 years were the ones who presented the highest increase in incidence. More wide-ranging epidemiological studies therefore become necessary for defining the factors that are possibly related to this excessive increase in breast cancer incidence, in certain specific segments of the female population.

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Authors and Affiliations

  1. Gynecology and Breast Service of Hospital Araújo Jorge, Goiás Anticancer Association (ACCG), Rua 239, 181, Setor Universitário, 74605-070, Goiania, GO, Brazil

    Ruffo Freitas-Junior

  2. Radiotherapy Service of Hospital Araújo Jorge, Goias, Brazil

    Nilceana Maya Aires Freitas

  3. Population-based Cancer Registry of Goiânia, Goiania, GO, Brazil

    Maria Paula Curado, Edesio Martins & Carleane Maciel Bandeira e Silva

  4. International Agency for Research on Cancer IARC, Lyon Cedex 08, France

    Maria Paula Curado

  5. Department of Pathology and Imaging, School of Medicine, Federal University of Goiás (UFG), Goias, Brazil

    Marise Amaral Rebouças Moreira

Authors
  1. Ruffo Freitas-Junior
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  2. Nilceana Maya Aires Freitas
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  3. Maria Paula Curado
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  4. Edesio Martins
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  5. Marise Amaral Rebouças Moreira
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  6. Carleane Maciel Bandeira e Silva
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Correspondence to Ruffo Freitas-Junior.

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Freitas-Junior, R., Freitas, N.M.A., Curado, M.P. et al. Variations in breast cancer incidence per decade of life (Goiânia, GO, Brazil): 16-year analysis. Cancer Causes Control 19, 681–687 (2008). https://doi.org/10.1007/s10552-008-9131-z

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  • DOI: https://doi.org/10.1007/s10552-008-9131-z

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