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Consumption of different types of meat and the risk of renal cancer: meta-analysis of case–control studies

Cancer Causes & Control volume 18, pages 125–133 (2007)Cite this article

An Erratum to this article was published on 01 March 2007

Abstract

Background

Kidney cancers account for almost 2% of all cancers worldwide, with 150,000 new cases and 78,000 deaths from the disease occurring annually. An increase in the incidence of kidney neoplasm in western countries was noticed in the past few years. Between 1988 and 1992, the incidence of renal cancer per 100,000 person-year among males in USA, Norway, and France was 34.1, 9.00, and 16.10, respectively. Among females in the same countries, it was 5.70, 5.00, and 7.30, respectively. Although several individual case–control studies examined the association of meat intake and renal cancer risk, the results were inconsistent because of the insufficient statistical power of the individual studies. Therefore, the following meta-analysis was designed to help in clarifying the association.

Methods

Electronic search of MEDLINE, OVID, and PUBMED databases which have articles published between (1966 and 2006) was conducted to select studies for this meta-analysis.

Statistical analysis

Fixed and random-effects meta-analytical techniques were used to estimate the overall association between meat consumption and kidney cancer.

Results

Thirteen case–control studies were found. This meta-analysis supported a positive relationship between meat consumption and risk of renal cancer. Summary results indicated that there was from 20% to 22% higher risk of renal cancer among those in the highest relative to the lowest category of poultry and processed meat consumption. Consumption of all meat and red meat was associated with 27% and 30% higher risk, respectively. The increased risks were statistically significant.

Conclusions

Increased consumption of all meat, red meat, poultry, and processed meat is associated with an increase risk of kidney cancer. Reduction of meat consumption is an important approach to decreasing the incidence of kidney cancer in the general population.

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Authors and Affiliations

  1. Epidemiology Department, Tulane University School of Public Health & Tropical Medicine, 1440 Canal Street Suite 2000, New Orleans, LA, 70112, USA

    Mohammed F. Faramawi, M. Whitney Fry, Macodu Sall & Zhou Yi

  2. University of North Texas Health Science Center, Fort Worth, USA

    Eric Johnson & Zhou Yi

Authors
  1. Mohammed F. Faramawi
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  2. Eric Johnson
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  3. M. Whitney Fry
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  4. Macodu Sall
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  5. Zhou Yi
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Correspondence to Mohammed F. Faramawi.

Additional information

An erratum to this article is available at http://dx.doi.org/10.1007/s10552-007-0120-4.

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Faramawi, M.F., Johnson, E., Fry, M.W. et al. Consumption of different types of meat and the risk of renal cancer: meta-analysis of case–control studies. Cancer Causes Control 18, 125–133 (2007). https://doi.org/10.1007/s10552-006-0104-9

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Keywords

  • Meta-analysis
  • Meat
  • Renal neoplasm
  • Case–control studies