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Health-related quality of life of Iranian breast cancer patients: a meta-analysis and systematic review

Breast Cancer Research and Treatment volume 170, pages 205–212 (2018)Cite this article

Abstract

Purpose

Quality of life is the most important psychological factor affecting breast cancer patients. This study aimed to examine the health related quality of life of breast cancer patients in Iran.

Methods

International (PubMed, Web of science, Scopus and Google scholar) and national (SID, Magiran) databases were searched for related studies to September 2017. The quality of the articles was evaluated using the Hoy tool.

Results

Out of 232 initial studies, 18 studies performed on 2263 people were included in the final stage of the study. Based on the EORTC-QLQ-C30 and random effect method, the pooled mean score of quality of life in 1073 people was 57.88 (95% CI 48.26–67.41, I2 = 97.90%) and the pooled mean score of quality of life based on WHOQOL-BREF in 357 people was 66.79 (95% CI 45.96–87.62, I2 = 99.50%).

Conclusion

According to the results of the study, a moderate level of quality of life in women with breast cancer was indicated. Therefore, the use of multidimensional approaches can improve their quality of life.

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References

  1. Torre LA, Siegel RL, Ward EM, Jemal A (2016) Global cancer incidence and mortality rates and trends—an update. Cancer Epidemiol Biomark Prev 25(1):16–27

    Article  Google Scholar 

  2. Jafari-Koshki T, Schmid VJ, Mahaki B (2014) Trends of breast cancer incidence in Iran during 2004-2008: a Bayesian space-time model. Asian Pac J Cancer Prev: APJCP 15(4):1557–1561

    Article  PubMed  Google Scholar 

  3. Cancer IAfRo, Organization WH (2016) IARC handbooks of cancer prevention volume 15-breast cancer screening. Int Agency Res Cancer,

  4. DeSantis CE, Bray F, Ferlay J, Lortet-Tieulent J, Anderson BO, Jemal A (2015) International variation in female breast cancer incidence and mortality rates. Cancer Epidemiol Biomark Prev 24(10):1495–1506

    Article  Google Scholar 

  5. DeSantis C, Ma J, Bryan L (2013) Jemal A (2014) Breast cancer statistics. CA Cancer J Clin 64(1):52–62

    Article  PubMed  Google Scholar 

  6. Lamyian M, Heidarnia A, Ahmadi F, Faghihzadeh S, AguilarVafaie M (2008) Women’s prospect of breast cancer early detection behavior: a qualitative research. J Birjand Univ Med Sci 15(3):88–102

    Google Scholar 

  7. Park K (2002) Preventive and social medicine. M/s. Banarsidas bhanot publishers, Jabalpur (India)

    Google Scholar 

  8. Testa MA, Simonson DC (1996) Assessment of quality-of-life outcomes. N Engl J Med 334(13):835–840

    Article  PubMed  CAS  Google Scholar 

  9. Park K (2007) Park’s textbook of preventive and social medicine

  10. Barbotte E, Guillemin F, Chau N (2001) Prevalence of impairments, disabilities, handicaps and quality of life in the general population: a review of recent literature. Bull World Health Organ 79(11):1047–1055

    PubMed  PubMed Central  CAS  Google Scholar 

  11. Alipour F, Sajadi H, Foruzan A, Biglarian A, Jalilian A (2008) Elderly quality of life in Tehran’s district two. Iran J Ageing 3(3):75–83

    Google Scholar 

  12. Kamali M, Arjmand HM, Ahangari M (2008) A Study of quality of life among older people with hypertension and low back pain. Salmand 3(7):26–32

    Google Scholar 

  13. Mousavi S, Asri M (2003) Educational requirements of patients with cancer during chemotherapy and radiotherapy for their self-care. JBUMS 5(1):17–20

    Google Scholar 

  14. Moher D, Liberati A, Tetzlaff J, Altman DG, Group P (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 6(7):e1000097

    Article  Google Scholar 

  15. McGowan J, Sampson M, Salzwedel DM, Cogo E, Foerster V, Lefebvre C (2016) Press peer review of electronic search strategies: 2015 guideline statement. J Clin Epidemiol 75:40–46

    Article  PubMed  Google Scholar 

  16. Hoy D, Brooks P, Woolf A, Blyth F, March L, Bain C, Baker P, Smith E, Buchbinder R (2012) Assessing risk of bias in prevalence studies: modification of an existing tool and evidence of interrater agreement. J Clin Epidemiol 65(9):934–939

    Article  PubMed  Google Scholar 

  17. Jafari N, Farajzadegan Z, Zamani A, Bahrami F, Emami H, Loghmani A (2013) Spiritual well-being and quality of life in Iranian women with breast cancer undergoing radiation therapy. Support Care Cancer 21(5):1219–1225. https://doi.org/10.1007/s00520-012-1650-1

    Article  PubMed  Google Scholar 

  18. Khalili N, Farajzadegan Z, Mokarian F, Bahrami F (2013) Coping strategies, quality of life and pain in women with breast cancer. Iranian J Nurs Midwifery Res 18(2):105

    Google Scholar 

  19. Moradi R, Roudi MA, Kiani MM, Rigi SAM, Mohammadi M, Keshvari M, Hosseini M (2017) Investigating the relationship between self-efficacy and quality of life in breast cancer patients receiving chemical therapy. Bali Med J 6(1):6–11. https://doi.org/10.15562/bmj.v6i1.358

    Article  Google Scholar 

  20. Musarezaie A, Ghasemi TM, Esfahani HN (2012) Investigation the quality of life and its relation with clinical and demographic characteristics in women with breast cancer under chemotherapy. Int J Prev Med 3(12):853–859

    Article  PubMed  PubMed Central  Google Scholar 

  21. Sadoughi M, Mehrzad V, Mohammad Salehi Z (2017) The relationship between psychological capital and quality of life among patients with breast cancer. Razi J Med Sci 24(156):111–119

    Google Scholar 

  22. Kiaei M, Ferdosi M, Moradi R, Chelongar Q, Ahmadzadeh MS, Bahmanziari N (2016) Association between self-efficacy and quality of life in women with breast cancer undergoing chemotherapy. J Qazvin Univ Med Sci 20(2):58–65

    Google Scholar 

  23. HasanpourDehkordi A (2006) Factors affecting quality of life in cancer patients under chemotherapy in Tehran (2004). J Kermanshah Univ Med Sci 10 (2

  24. Montazeri A, Vahdaninia M, Harirchi I, Ebrahimi M, Khaleghi F, Jarvandi S (2008) Quality of life in patients with breast cancer before and after diagnosis: an eighteen months follow-up study. BMC Cancer 8:330. https://doi.org/10.1186/1471-2407-8-330

    Article  PubMed  PubMed Central  Google Scholar 

  25. Najafi F, Nedjat S, Zendehdel K, Mirzania M, Montazeri A (2016) Self-reported versus proxy reported quality of life for breast cancer patients in the Islamic Republic of Iran. East Mediterr Health J 22(11):786–793

    Article  Google Scholar 

  26. Rohani C, Abedi HA, Omranipour R, Langius-Eklof A (2015) Health-related quality of life and the predictive role of sense of coherence, spirituality and religious coping in a sample of Iranian women with breast cancer: a prospective study with comparative design. Health Qual Life Outcomes 13:40. https://doi.org/10.1186/s12955-015-0229-1

    Article  PubMed  PubMed Central  Google Scholar 

  27. Zamanian H, Eftekhar-Ardebili H, Eftekhar-Ardebili M, Shojaeizadeh D, Nedjat S, Taheri-Kharameh Z, Daryaafzoon M (2015) Religious coping and quality of life in women with breast cancer. Asian Pac J Cancer Prev APJCP 16(17):7721–7725

    Article  PubMed  Google Scholar 

  28. Hatam N, Bastani P, Ahmadloo N, Kiadaliri AA (2012) Health related quality of life in breast cancer patients undergoing current chemotherapy protocols. J Kerman Univ Med Sci 19(1):49–58

    Google Scholar 

  29. Safaee A, Moghimi-Dehkordi B, Zeighami B, Tabatabaee H, Pourhoseingholi M (2008) Predictors of quality of life in breast cancer patients under chemotherapy. Indian J Cancer 45(3):107

    Article  PubMed  CAS  Google Scholar 

  30. Bagheri M, Mazaheri M (2015) Body image and quality of life in female patients with breast cancer and healthy women. J Midwifery Reprod Health 3(1):285–292

    Google Scholar 

  31. Shandiz FH, Karimi FZ, Anbaran ZK, Abdollahi M, Rahimi N, Ghasemi M (2017) Investigating the quality of life and the related factors in iranian women with breast cancer. Asian Pac J Cancer Prev 18(8):2089–2092

    PubMed Central  Google Scholar 

  32. Hosseini SM (2014) Quality of life, pain and treatment acceptance in women with breast cancer in Chaharamahal and Bakhtiari. Iran Q J Breast Dis 6(4):52–59

    Google Scholar 

  33. Monfared A, Pakseresht S, Ghanbari Khanghah A, Atrkar-Roshan Z (2013) Health-Related Quality of Life and its related factors among women with breast cancer. J Holist Nurs Midwifery 23(2):52–62

    Google Scholar 

  34. Ayatollahi H (2013) Quality of life in breast cancer patients: study in the Omid cancer research center– Urmia. Iran Q J Breast Dis 5(4):35–43

    Google Scholar 

  35. Montazeri A, Goshtasebi A, Vahdaninia M, Gandek B (2005) The short form health survey (SF-36): translation and validation study of the Iranian version. Q Life Res 14(3):875–882

    Article  Google Scholar 

  36. Nejat S, Montazeri A, Holakouie Naieni K, Mohammad K, Majdzadeh S (2006) The world health organization quality of Life (WHOQOL-BREF) questionnaire: translation and validation study of the Iranian version. J Sch Publ Health Inst Publ Health Res 4(4):1–12

    Google Scholar 

  37. Montazeri A, Harirchi I, Vahdani M, Khaleghi F, Jarvandi S, Ebrahimi M, Haji-Mahmoodi M (1999) The European organization for research and treatment of cancer quality of life questionnaire (EORTC QLQ-C30): translation and validation study of the Iranian version. Support Care Cancer 7(6):400–406

    Article  PubMed  CAS  Google Scholar 

  38. Rafiei N, Sharifian Sani M, Rafiey H, Behnampour N, Foroozesh K (2014) Reliability and Validity of Persian Version of. J Mazandaran Univ Med Sci 24(116):75–83

    Google Scholar 

  39. Saleha S, Shakeel A, Shumaila E, Shazia R, Rashid R, Ibrahim M (2012) An assessment of quality of life in breast cancer patients using EORTC QLQ C30/+ Br 23 questionnaire. Iran J Cancer Prev 3(2):98–104

    Google Scholar 

  40. Almutairi KM, Mansour EA, Vinluan JM (2016) A cross-sectional assessment of quality of life of breast cancer patients in Saudi Arabia. Publ Health 136:117–125. https://doi.org/10.1016/j.puhe.2016.03.008

    Article  CAS  Google Scholar 

  41. Ahn S, Park B, Noh D, Nam S, Lee E, Lee M, Kim S, Lee K, Park S, Yun Y (2006) Health-related quality of life in disease-free survivors of breast cancer with the general population. Ann Oncol 18(1):173–182

    Article  PubMed  Google Scholar 

  42. Hopwood P, Haviland J, Mills J, Sumo G, Bliss JM (2007) The impact of age and clinical factors on quality of life in early breast cancer: an analysis of 2208 women recruited to the UK START Trial (standardisation of breast radiotherapy trial). The Breast 16(3):241–251

    Article  PubMed  Google Scholar 

  43. Waldmann A, Pritzkuleit R, Raspe H, Katalinic A (2007) The OVIS study: health related quality of life measured by the EORTC QLQ-C30 and-BR23 in German female patients with breast cancer from Schleswig-Holstein. Q Life Res 16(5):767–776

    Article  CAS  Google Scholar 

  44. Rabin EG, Heldt E, Hirakata VN, Fleck MP (2008) Quality of life predictors in breast cancer women. Eur J Oncol Nurs 12(1):53–57

    Article  PubMed  Google Scholar 

  45. Purkayastha D, Venkateswaran C, Nayar K, Unnikrishnan U (2017) Prevalence of depression in breast cancer patients and its association with their quality of life: a cross-sectional observational study. Indian J Palliat Care 23(3):268

    Article  PubMed  PubMed Central  Google Scholar 

  46. Sammarco A (2001) Perceived social support, uncertainty, and quality of life of younger breast cancer survivors. Cancer Nurs 24(3):212–219

    Article  PubMed  CAS  Google Scholar 

  47. Avis NE, Crawford S, Manuel J (2005) Quality of life among younger women with breast cancer. J Clin Oncol 23(15):3322–3330

    Article  PubMed  Google Scholar 

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Author information

Affiliations

  1. Clinical Immunology Research Center, Ali-ebne Abitaleb Hospital, Zahedan University of Medical Sciences, Zahedan, Iran

    Salehoddin Bouya

  2. Department of Midwifery, School of Nursing and Midwifery, Zabol University of Medical Science, Zabol, Iran

    Maryam koochakzai & Mahin Badakhsh

  3. Student Research Committee, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Hosein Rafiemanesh

  4. Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Hosein Rafiemanesh

  5. Zabol University of Medical Sciences, Zabol, Iran

    Abbas Balouchi & Safiyeh Taheri

  6. Student Research Committee, Nursing and Midwifery School, University of Medical Sciences, Tehran, Iran

    Abbas Balouchi

  7. Midwifery Department, School of Nursing and Midwifery, Iranshahr University of Medical Sciences, Iranshahr, Iran

    Mahnaz Didehvar

Authors
  1. Salehoddin Bouya
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  2. Maryam koochakzai
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Correspondence to Mahin Badakhsh.

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All procedures performed in the study described in this manuscript were in accordance with the ethical standards of the institutional and/or national research committee.

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Bouya, S., koochakzai, M., Rafiemanesh, H. et al. Health-related quality of life of Iranian breast cancer patients: a meta-analysis and systematic review. Breast Cancer Res Treat 170, 205–212 (2018). https://doi.org/10.1007/s10549-018-4750-x

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  • DOI: https://doi.org/10.1007/s10549-018-4750-x

Keywords

  • Quality of life
  • Breast Cancer
  • Iran
  • Systematic review