Skip to main content

Advertisement

SpringerLink
Log in

Low vitamin D status likely contributes to the link between periodontal disease and breast cancer

  • Letter to the Editor
  • Published:
Breast Cancer Research and Treatment Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Söder B, Yakob M, Meurman JH, Andersson LC, Klinge B, Söder P-Ö (2010) Periodontal disease may associate with breast cancer. Breast Cancer Res Treat. doi:10.1007/s10549-010-1221-4

  2. Lewis JR (1865) Exemptions from military service on account of loss of teeth. Dental Cosmos 7:240–242

    Google Scholar 

  3. Mellanby M, Pattison CL (1928) The action of vitamin D in preventing the spread and promoting the arrest of caries in children. Brit Med J 2:1079–1082

    Article  PubMed  CAS  Google Scholar 

  4. Mills CA (1937) Factors affecting the incidence of dental caries in population groups. J Dent Res 16:417–430

    Article  Google Scholar 

  5. Amano Y, Komiyama K, Makishima M (2009) Vitamin D and periodontal disease. J Oral Sci 51(1):11–20

    Article  PubMed  Google Scholar 

  6. Grant WB, Boucher BJ (2010) Are Hill’s criteria for causality satisfied for vitamin D and periodontal disease? Derm Endocrinol 2(1):30–36

    Article  CAS  Google Scholar 

  7. Gombart AF (2009) The vitamin D-antimicrobial peptide pathway and its role in protection against infection. Future Microbiol 4(9):1151–1165

    Article  PubMed  CAS  Google Scholar 

  8. Hewison M (2011) Antibacterial effects of vitamin D. Nat Rev Endocrinol. doi:10.1038/nrendo.2010.226

  9. Tetlow LC, Woolley DE (2001) Expression of vitamin D receptors and matrix metalloproteinases in osteoarthritic cartilage and human articular chondrocytes in vitro. Osteoarthr Cartil 9(5):423–431

    Article  PubMed  CAS  Google Scholar 

  10. Timms PM, Mannan N, Hitman GA, Noonan K, Mills PG, Syndercombe-Court D et al (2002) Circulating MMP9, vitamin D and variation in the TIMP-1 response with VDR genotype: mechanisms for inflammatory damage in chronic disorders? QJM 95(12):787–796

    Article  PubMed  CAS  Google Scholar 

  11. Grant WB, Garland CF (2006) The association of solar ultraviolet B (UVB) with reducing risk of cancer: multifactorial ecologic analysis of geographic variation in age-adjusted cancer mortality rates. Anticancer Res 26(4):2687–2699

    PubMed  CAS  Google Scholar 

  12. Porojnicu AC, Lagunova Z, Robsahm TE, Berg JP, Dahlback A, Moan J (2007) Changes in risk of death from breast cancer with season and latitude: sun exposure and breast cancer survival in Norway. Breast Cancer Res Treat 102(3):323–328

    Article  PubMed  Google Scholar 

  13. Abbas S, Linseisen J, Slanger T, Kropp S, Mutschelknauss E, Flesch-Janys D, Chang-Claude J (2008) Serum 25-hydroxyvitamin D and risk of postmenopausal breast cancer—results of a large case–control study. Carcinogenesis 29(1):93–99

    Article  PubMed  CAS  Google Scholar 

  14. Almquist M, Bondeson AG, Bondeson L, Malm J, Manjer J (2010) Serum levels of vitamin D, PTH, calcium and breast cancer risk—a prospective nested case–control study. Int J Cancer 127(9):2159–2168

    Article  PubMed  CAS  Google Scholar 

  15. Grant WB (2010) Relation between prediagnostic serum 25-hydroxyvitamin D level and incidence of breast, colorectal, and other cancers. J Photochem Photobiol B 101(2):130–136

    Article  PubMed  CAS  Google Scholar 

  16. Guillot X, Semerano L, Saidenberg-Kermanac’h N, Falgarone G, Boissier MC (2010) Vitamin D and inflammation. Jt Bone Spine 77(6):552–557

    Article  CAS  Google Scholar 

  17. Goldberg JE, Schwertfeger KL (2010) Proinflammatory cytokines in breast cancer: mechanisms of action and potential targets for therapeutics. Curr Drug Targets 11(9):1133–1146

    Article  PubMed  CAS  Google Scholar 

Download references

Acknowledgments

WBG receives or has received funding from the UV Foundation (McLean, VA), the Sunlight Research Forum (Veldhoven), Bio-Tech-Pharmacal (Fayetteville, AR), and the Vitamin D Council (San Luis Obispo, CA).

Author information

Authors and Affiliations

  1. Sunlight, Nutrition, and Health Research Center (SUNARC), P.O. Box 641603, San Francisco, CA, 94164-1603, USA

    William B. Grant

  2. Centre for Diabetes, Bart’s & The London School of Medicine and Dentistry, Queen Mary University of London, Blizard Institute of Cell and Molecular Science, 4 Newark Street, London, E1 2AT, UK

    Barbara J. Boucher

Authors
  1. William B. Grant
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Barbara J. Boucher
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to William B. Grant.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Grant, W.B., Boucher, B.J. Low vitamin D status likely contributes to the link between periodontal disease and breast cancer. Breast Cancer Res Treat 128, 907–908 (2011). https://doi.org/10.1007/s10549-011-1458-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10549-011-1458-6

Keywords

Search

Navigation