Skip to main content

Advertisement

SpringerLink
Log in

Factor V Leiden and prothrombin G20210A polymorphisms are not associated with disease-free survival in breast cancer

  • Letter to the Editor
  • Published:
Breast Cancer Research and Treatment Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Winter PC (2006) The pathogenesis of venous thromboembolism in cancer: emerging links with tumor biology. Hematol Oncol 24:126–133. doi:10.1002/hon.785

    Article  PubMed  CAS  Google Scholar 

  2. Paspatis GA, Sfyridaki A, Papanikolaou N, Triantafyllou K, Livadiotaki A, Kapsoritakis A et al (2002) Resistance to activated protein C, factor V Leiden and prothrombin G20210A variant in patients with colorectal cancer. Pathophysiol Haemost Thromb 32:2–7. doi:10.1159/000057282

    Article  PubMed  CAS  Google Scholar 

  3. Samonakis DN, Koutroubakis IE, Sfiridaki A, Malliaraki N, Antoniou P, Romanos J et al (2004) Hypercoagulable states in patients with hepatocellular carcinoma. Dig Dis Sci 49:854–858. doi:10.1023/B:DDAS.0000030099.13397.28

    Article  PubMed  CAS  Google Scholar 

  4. Vairaktaris E, Yapijakis C, Wiltfang J, Ries J, Vylliotis A, Derka S et al (2005) Are factor V and prothrombin mutations associated with increased risk of oral cancer? Anticancer Res 25:2561–2565

    PubMed  CAS  Google Scholar 

  5. Battistelli S, Stefanoni M, Genovese A, Vittoria A, Cappelli R, Roviello F (2006) Prevalence of factor V Leiden and prothrombin G20210A in patients with gastric cancer. World J Gastroenterol 12:4179–4180

    PubMed  CAS  Google Scholar 

  6. Tormene D, Beltramello P, Perlati M, Brandolin B, Barbar S, De Toffoli G, Simioni P (2008) The risk of cancer progression in women with gynecological malignancies and thrombophilic polymorphisms: a pilot case-control study. Clin Appl Thromb Hemost (Epub ahead of print). doi: 10.1177/1076029608317941

  7. Pihusch R, Danzl G, Scholz M, Harich D, Pihusch M, Lohse P et al (2002) Impact of thrombophilic gene mutations on thrombosis risk in patients with gastrointestinal carcinoma. Cancer 94:3120–3126. doi:10.1002/cncr.10590

    Article  PubMed  CAS  Google Scholar 

  8. Brüggemann LW, Versteeg HH, Niers TM, Reitsma PH, Spek CA (2008) Experimental melanoma metastasis in lungs of mice with congenital coagulation disorders. J Cell Mol Med (Epub ahead of print)

  9. Klerk CPW, Smorenburg SM, Spek CA, Van Noorden CJF (2007) Colon cancer metastasis in mouse liver is not affected by hypercoagulability due to Factor V Leiden mutation. J Cell Mol Med 11:561–568. doi:10.1111/j.1582-4934.2007.00046.x

    Article  PubMed  CAS  Google Scholar 

  10. Eroglu A, Ulu A, Cam R, Kurtman C, Akar N (2007) Prevalence of factor V 1691G-A (Leiden) and prothrombin G20210A polymorphisms and the risk of venous thrombosis among cancer patients. J Thromb Thrombolysis 23:31–34. doi:10.1007/s11239-006-9001-z

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of General Surgery, Ankara University Medical School, Ankara, Turkey

    Aydan Eroglu & Ragip Çam

  2. Department of Pediatric Molecular Genetic, Ankara University Medical School, Ankara, Turkey

    Yonca Eğin & Nejat Akar

Authors
  1. Aydan Eroglu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ragip Çam
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yonca Eğin
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Nejat Akar
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Aydan Eroglu.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Eroglu, A., Çam, R., Eğin, Y. et al. Factor V Leiden and prothrombin G20210A polymorphisms are not associated with disease-free survival in breast cancer. Breast Cancer Res Treat 116, 619–620 (2009). https://doi.org/10.1007/s10549-008-0177-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10549-008-0177-0

Keywords

Search

Navigation