Paraneoplastic neurological syndromes and breast cancer. Regression of paraneoplastic neurological sensorimotor neuropathy in a patient with metastatic breast cancer treated with capecitabine: a case study and mini-review of the literature

  • Alessandro M. MinisiniEmail author
  • Giada Pauletto
  • Paolo Bergonzi
  • Gianpiero Fasola


Paraneoplastic neurological syndromes are a rare complication of breast cancer. Nevertheless, they may be clinically relevant leading to neurological impairment. Clinicians should be aware that these neurological disorders could even precede the diagnosis of breast cancer. Here we present the case of a female patient with advanced breast cancer who developed paraneoplastic sensorimotor neuropathy. Treatment with capecitabine lead to clinical amelioration. A review of the literature on the paraneoplastic neurological syndromes in breast cancer is also included.


Neurological paraneoplastic syndrome Autoantibodies Sensorimotor neuropathy Breast cancer Capecitabine 


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Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  • Alessandro M. Minisini
    • 1
    Email author
  • Giada Pauletto
    • 2
  • Paolo Bergonzi
    • 2
  • Gianpiero Fasola
    • 1
  1. 1.Department of Medical Oncology University and S.M. Misericordia HospitalUdineItaly
  2. 2.Department of NeurologyUniversity and S.M. Misericordia HospitalUdineItaly

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