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Synchronous bilateral ductal carcinoma in situ of the male breast associated with gynecomastia in a 30-year-old patient following repeated injections of stanozolol

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Summary

We report a rare case of synchronous bilateral and multifocal ductal carcinoma in situ (DCIS) in a 30-year-old patient operated on for gynecomastia following repeated injections of stanozolol, a non-aromatizable androgen. The familial medical history was negative for breast cancer and work-up of serum hormone levels was normal. The patient underwent a modified radical mastectomy without axilla dissection 6 weeks following the primary procedure and recovered uneventfully. The role of synthetic androgens in the development of male breast neoplasia warrants further scrutiny.

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Authors and Affiliations

  1. Department of Surgery, Spital Uster, Uster, Switzerland

    Ralph F. Staerkle, Philipp M. Lenzlinger & A. Melcher

  2. Endocrine Practice, Maennedorf, Switzerland

    Stephan L. Suter

  3. Institute of Clinical Pathology, University Hospital of Zurich, Zurich, Switzerland

    Zsuzsanna Varga

  4. Chirurgische Klinik Spital Uster, Brunnenstrasse 42, 8610, Uster, Switzerland

    Philipp M. Lenzlinger

Authors
  1. Ralph F. Staerkle
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  2. Philipp M. Lenzlinger
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  3. Stephan L. Suter
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  4. Zsuzsanna Varga
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  5. A. Melcher
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Correspondence to Philipp M. Lenzlinger.

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Staerkle, R.F., Lenzlinger, P.M., Suter, S.L. et al. Synchronous bilateral ductal carcinoma in situ of the male breast associated with gynecomastia in a 30-year-old patient following repeated injections of stanozolol. Breast Cancer Res Treat 97, 173–176 (2006). https://doi.org/10.1007/s10549-005-9107-6

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  • DOI: https://doi.org/10.1007/s10549-005-9107-6

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