Brain Topography

, Volume 27, Issue 4, pp 480–499

An Overview of Stimulus-Specific Adaptation in the Auditory Thalamus


DOI: 10.1007/s10548-013-0342-6

Cite this article as:
Antunes, F.M. & Malmierca, M.S. Brain Topogr (2014) 27: 480. doi:10.1007/s10548-013-0342-6


In the auditory brain, some populations of neurons exhibit stimulus-specific adaptation (SSA), whereby they adapt to frequently occurring stimuli but retain sensitivity to stimuli that are rare. SA has been observed in auditory structures from the midbrain to the primary auditory cortex (A1) and has been proposed to be a precursor to the generation of deviance detection. SSA is strongly expressed in non-lemniscal regions of the medial geniculate body (MGB), the principal nucleus of the auditory thalamus. In this account we review the state of the art of SSA research in the MGB, highlighting the importance of this auditory centre in detecting sounds that may be relevant for survival.


Auditory Thalamus Deviance detection SSA MMN Corticofugal modulation 

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Auditory Neurophysiology Unit, Laboratory for the Neurobiology of Hearing, Institute of Neuroscience of Castilla y LeónUniversity of SalamancaSalamancaSpain
  2. 2.Department of Cell Biology and Pathology, Faculty of MedicineUniversity of SalamancaSalamancaSpain

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