Biomedical Microdevices

, 19:87 | Cite as

Passive, wireless transduction of electrochemical impedance across thin-film microfabricated coils using reflected impedance

  • Alex Baldwin
  • Lawrence Yu
  • Madelina Pratt
  • Kee Scholten
  • Ellis Meng
Article
  • 214 Downloads

Abstract

A new method of wirelessly transducing electrochemical impedance without integrated circuits or discrete electrical components was developed and characterized. The resonant frequency and impedance magnitude at resonance of a planar inductive coil is affected by the load on a secondary coil terminating in sensing electrodes exposed to solution (reflected impedance), allowing the transduction of the high-frequency electrochemical impedance between the two electrodes. Biocompatible, flexible secondary coils with sensing electrodes made from gold and Parylene C were microfabricated and the reflected impedance in response to phosphate-buffered saline solutions of varying concentrations was characterized. Both the resonant frequency and impedance at resonance were highly sensitive to changes in solution conductivity at the secondary electrodes, and the effects of vertical separation, lateral misalignment, and temperature changes were also characterized. Two applications of reflected impedance in biomedical sensors for hydrocephalus shunts and glucose sensing are discussed.

Keywords

Electrochemical impedance Reflected impedance Passive Wireless Sensor Coils Inductive coupling Glucose sensing Hydrocephalus 

Notes

Acknowledgements

The authors would like to thank Ewina Pun and Sam Huynh for their help with device characterization, Dr. Donghai Zhu of the Keck Photonics Lab for assistance with fabrication, and all the members of the Biomedical Microsystems Lab of USC for their advice and support. This work was supported in part by the National Science Foundation under award EFRI-1332394.

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Copyright information

© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  • Alex Baldwin
    • 1
  • Lawrence Yu
    • 1
  • Madelina Pratt
    • 1
  • Kee Scholten
    • 1
  • Ellis Meng
    • 1
    • 2
  1. 1.Department of Biomedical Engineering, Viterbi School of EngineeringUniversity of Southern CaliforniaLos AngelesUSA
  2. 2.Ming Hsieh Department of Electrical Engineering, Viterbi School of EngineeringUniversity of Southern CaliforniaLos AngelesUSA

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