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A flexible layout design method for passive micromixers

Biomedical Microdevices volume 14, pages 929–945 (2012)Cite this article

Abstract

This paper discusses a flexible layout design method of passive micromixers based on the topology optimization of fluidic flows. Being different from the trial and error method, this method obtains the detailed layout of a passive micromixer according to the desired mixing performance by solving a topology optimization problem. Therefore, the dependence on the experience of the designer is weaken, when this method is used to design a passive micromixer with acceptable mixing performance. Several design disciplines for the passive micromixers are considered to demonstrate the flexibility of the layout design method for passive micromixers. These design disciplines include the approximation of the real 3D micromixer, the manufacturing feasibility, the spacial periodic design, and effects of the Péclet number and Reynolds number on the designs obtained by this layout design method. The capability of this design method is validated by several comparisons performed between the obtained layouts and the optimized designs in the recently published literatures, where the values of the mixing measurement is improved up to 40.4% for one cycle of the micromixer.

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Acknowledgements

This work is supported by the National Natural Science Foundation of China (No.50975272, No. 11034007), the 863 Program (No.2012AA040503) and the hundred talent project in Chinese Academy of Sciences. The authors are also grateful to the reviewers’ kind attention and valuable suggestions.

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Affiliations

  1. Changchun Institute of Optics, Fine Mechanics and Physics (CIOMP), Chinese Academy of Sciences, 130033, Changchun, China

    Yongbo Deng, Zhenyu Liu, Ping Zhang, Yongshun Liu, Qingyong Gao & Yihui Wu

  2. Graduate University of Chinese Academy of Sciences, Changchun, China

    Yongshun Liu & Qingyong Gao

Authors
  1. Yongbo Deng
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  2. Zhenyu Liu
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  3. Ping Zhang
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  4. Yongshun Liu
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  5. Qingyong Gao
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  6. Yihui Wu
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Correspondence to Zhenyu Liu or Yihui Wu.

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Deng, Y., Liu, Z., Zhang, P. et al. A flexible layout design method for passive micromixers. Biomed Microdevices 14, 929–945 (2012). https://doi.org/10.1007/s10544-012-9672-5

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Keywords

  • Passive micromixer
  • Layout design
  • Topology optimization
  • Manufacturing feasibility
  • Periodic layout