Biotechnology Letters

, Volume 40, Issue 2, pp 237–248 | Cite as

Magnetic immobilization of bacteria using iron oxide nanoparticles

  • Dinali Ranmadugala
  • Alireza Ebrahiminezhad
  • Merilyn Manley-Harris
  • Younes Ghasemi
  • Aydin BerenjianEmail author


Bacterial cell immobilization is a novel technique used in many areas of biosciences and biotechnology. Iron oxide nanoparticles have attracted much attention in bacterial cell immobilization due to their unique properties such as superparamagnetism, large surface area to volume ratio, biocompatibility and easy separation methodology. Adhesion is the basis behind many immobilization techniques and various types of interactions determine bacterial adhesion. Efficiency of bacterial cell immobilization using iron oxide nanoparticles (IONs) generally depends on the physicochemical properties of the IONs and surface properties of bacterial cells as well as environmental/culture conditions. Bacteria exhibit various metabolic responses upon interaction with IONs, and the potential applications of iron oxide nanoparticles in bacterial cell immobilization will be discussed in this work.


Biodetection Biofilm control Bioprocess engineering Environmental remediation Magnetic immobilization Superparamagnetism 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Authors and Affiliations

  • Dinali Ranmadugala
    • 1
  • Alireza Ebrahiminezhad
    • 2
    • 3
  • Merilyn Manley-Harris
    • 1
  • Younes Ghasemi
    • 3
  • Aydin Berenjian
    • 1
    Email author
  1. 1.Faculty of Science & EngineeringUniversity of WaikatoHamiltonNew Zealand
  2. 2.Department of Medical Biotechnology, School of Medicine, and Noncommunicable Diseases Research CentreFasa University of Medical SciencesFasaIran
  3. 3.Pharmaceutical Sciences Research CenterShiraz University of Medical SciencesShirazIran

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