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High-yield production of erythritol from raw glycerol in fed-batch cultures of Yarrowia lipolytica

Biotechnology Letters volume 31, pages 377–380 (2009)Cite this article

Abstract

An acetate-negative mutant of Yarrowia lipolytica Wratislavia K1 was selected that, when grown with 300 g raw glycerol l−1 at pH 3, produced 170 g erythritol l−1 after 7 days, corresponding to a 56% yield and a productivity of 1 g l−1 h−1. The Wratislavia K1 strain did not produce citric acid.

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Acknowledgment

This work was financed by the Ministry of Sciences and Higher Education of Poland under Project No. 2P06T 044 30.

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Affiliations

  1. Department of Biotechnology and Food Microbiology, Wroclaw University of Environmental and Life Sciences, Norwida 25, 50-375, Wroclaw, Poland

    Waldemar Rymowicz, Anita Rywińska & Marta Marcinkiewicz

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  1. Waldemar Rymowicz
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  2. Anita Rywińska
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  3. Marta Marcinkiewicz
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Correspondence to Waldemar Rymowicz.

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Rymowicz, W., Rywińska, A. & Marcinkiewicz, M. High-yield production of erythritol from raw glycerol in fed-batch cultures of Yarrowia lipolytica . Biotechnol Lett 31, 377–380 (2009). https://doi.org/10.1007/s10529-008-9884-1

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  • DOI: https://doi.org/10.1007/s10529-008-9884-1

Keywords

  • Erythritol production
  • Fed-batch
  • Raw glycerol
  • Yarrowia lipolytica