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Formulations for delivery of therapeutic proteins

Biotechnology Letters volume 31, pages 1–11 (2009)Cite this article

Abstract

Advances in biotechnology have now created a capacity to produce therapeutically active proteins on a commercial scale, opening the potential for their application in an array of disease conditions. The process of translation of the variety of different therapeutic proteins into the medicines used in clinics is now occurring. To assist in this translation, new formulations to deliver proteins could play an important role. These new formulations need to more adequately address the pharmacological and therapeutic requirement for each particular protein/peptide and, in that way, either improve present therapies or extend with new entries the current list of protein based medicines used in clinic.

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Notes

  1. http://www.fortical.com/docs/Professional_pi.pdf. Cited 29 July 2008.

  2. http://www.generex.com/index.php. Cited 16 July 2008.

  3. http://www.accesspharma.com/cobalamintargeted1.shtml. Accessed 29 July 2008.

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  1. Drug Delivery and Tissue Engineering Division, School of Pharmacy, University of Nottingham, University Park, NG7 2RD, UK

    Snjezana Stolnik & Kevin Shakesheff

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  1. Snjezana Stolnik
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  2. Kevin Shakesheff
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Correspondence to Snjezana Stolnik.

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Stolnik, S., Shakesheff, K. Formulations for delivery of therapeutic proteins. Biotechnol Lett 31, 1–11 (2009). https://doi.org/10.1007/s10529-008-9834-y

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  • DOI: https://doi.org/10.1007/s10529-008-9834-y

Keywords

  • Drug delivery
  • Intracellular delivery
  • Non-invasive
  • Protein delivery
  • Sustained release