Abstract
Monolauroyl maltose was synthesized by an immobilized lipase that catalyzed condensation of maltose and lauric acid in acetone using a batch reactor or a continuous stirred tank reactor. Mono- and di-lauroyl maltoses were identified by FT-IR, 1H NMR, 13C NMR and MS. Monolauroyl maltose was selectively synthesized in a continuous stirred tank reactor and no diester was detected. The highest concentration of monolauroyl maltose at 28 mmol/l was obtained in 250 ml acetone when maltose was added at 4 g/d and the molar ratio of lauric acid to maltose was fixed at 4:1 at a flow rate of 0.15 ml/min for both influx and effluent without supplement of fresh molecular sieve.
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Acknowledgement
This work was supported by National Hi-Technology Research & Development Programme of China (2006AA10Z312), HI-TECH Sustentation Fund of Jiangsu (BG2005015) and PCSIRT (IRT0532).
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Liu, Q., Jia, C., Kim, J.M. et al. Lipase-catalyzed selective synthesis of monolauroyl maltose using continuous stirred tank reactor. Biotechnol Lett 30, 497–502 (2008). https://doi.org/10.1007/s10529-007-9560-x
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DOI: https://doi.org/10.1007/s10529-007-9560-x