Skip to main content
Log in

Microwave-assisted extraction of embelin from Embelia ribes

  • Original Research Paper
  • Published:
Biotechnology Letters Aims and scope Submit manuscript

Abstract

A rapid and efficient microwave-assisted extraction (MAE) process for the selective extraction of embelin from Embelia ribes was developed. Solvent selection, microwave energy input and solid loading were optimized. The rate of extraction and purity of embelin depended upon the solvent used and exposure time to microwaves. Maximum MAE was achieved in acetone with total yield of 92% (w/w) embelin with 90% (w/w) purity with 1% (w/v) raw material loading at 150 W power level in 80 s. Non-polar solvents, such as hexane and dichloromethane, were not effective for the selective extraction of embelin.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  • Chauhan SK, Singh BP, Agarwal S (1999) Determination of embelin from Embelia ribes by high-performance thin layer chromatography. Indian Drugs 36:41–43

    CAS  Google Scholar 

  • Chitra M, Sukumar E, Suja V, Shyamala Devi CS (1994) Antitumour, antinflammatory and analgesic property of embelin, a plant product. Chemotherapy 40:109–113

    Article  PubMed  CAS  Google Scholar 

  • Engel LW, Straus SE (2002) Development of therapeutics: Opportunities within complementary and alternative medicine. Nat Rev: Drug Discov 1:229–237

    Article  CAS  Google Scholar 

  • Fornal J, Jaroch R, Kaczynska B, Ornowski A (1992) The influence of hydrothermal treatment of rapeseed on their selected physical properties and ability to crush during grinding. Fat Sci Technol 94:192–196

    Google Scholar 

  • Holzworth A, Lou J, Laibinis EP (1998) Enhanced microwave and steam heating of nonpolar solvents by dispersed magnetic nanoparticles. Ind Eng Chem Res 37:2701–2706

    Article  Google Scholar 

  • Kaufmann B, Christen P (2002) Recent extraction techniques for natural products: microwave-assisted extraction and pressurized solvent extraction. Phytochem Anal 13:105–113

    Article  PubMed  CAS  Google Scholar 

  • Kerem Z, German-Shashou H, Yarden O (2005) Microwave-assisted extraction of bioactive saponins from chickpea (Cicer arietinum L). J Sci Food Agric 85:406–412

    Article  CAS  Google Scholar 

  • Nikolovska-Coleska Z, Xu L, Hu Z, Tomita Y, Li P, Roller PP, Wang R, Fang X, Guo R, Zhang M, Lippman ME, Yang D, Wang S (2004) Discovery of embelin as a cell permeable, small-molecular weight inhibitor of XIAP through structure-based computational screening of a traditional herbal medicine three- dimensional structure database. J Med Chem 47:2430–2440

    Article  PubMed  CAS  Google Scholar 

  • Sakanishi K, Ikeyama N (1999) Comparison of hydrothermal decomposition reactivities of chitin and cellulose. Ind Eng Chem Res 38:2177–2181

    Article  CAS  Google Scholar 

  • Wang L, Weller CL (2006) Recent advances in extraction of nutraceuticals from plants. Trends Food Sci Technol 17:300–312

    Article  CAS  Google Scholar 

  • Xu M, Gui J, Fu H, Proksch P, Lin W, Li M (2005) Embelin derivatives and their anticancer activity through microtubule disassembly. Planta Med 71:944–948

    Article  PubMed  CAS  Google Scholar 

  • Zhou HY, Liu CZ (2006) Rapid determination of solanesol in tobacco by high- performance liquid chromatography with evaporative light scattering detection following microwave-assisted extraction. J Chromatogr B 835:119–122

    Google Scholar 

Download references

Acknowledgement

The author acknowledges the Council of Scientific and Industrial Research (CSIR), New Delhi, India for the financial assistance.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to C. Latha.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Latha, C. Microwave-assisted extraction of embelin from Embelia ribes . Biotechnol Lett 29, 319–322 (2007). https://doi.org/10.1007/s10529-006-9243-z

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10529-006-9243-z

Keywords

Navigation