Abstract
Yarrowia lipolytica converts methyl ricinoleate to γ-decalactone, a high-value fruity aroma compound. The highest amount of 3-hydroxy-γ-decalactone produced by the yeast (263 mg l-1) occurred by increasing the k L a up to 120 h−1 at atmospheric pressure; above it, its concentration decreased, suggesting a predominance of the activity of 3-hydroxyacyl-CoA dehydrogenase. Cultures were grown under high-pressure, i.e., under increased O2 solubility, but, although growth was accelerated, γ-decalactone production decreased. However, by applying 0.5 MPa during growth and biotransformation gave increased concentrations of dec−2-en-4-olide and dec-3-en-4-olide (70 mg l−1).
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Aguedo, M., Gomes, N., Garcia, E.E. et al. Decalactone Production by Yarrowia lipolytica under increased O2 Transfer Rates. Biotechnol Lett 27, 1617–1621 (2005). https://doi.org/10.1007/s10529-005-2517-z
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DOI: https://doi.org/10.1007/s10529-005-2517-z