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Characterisation of Hydrogel Gel Swelling by Molecular Exclusion

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Abstract

A facile method for the characterization of hydrogel swelling is described which is based on the determination of changes in the liquid phase concentration of an excluded tracer as gel swells in a constant volume system. The utility of this approach is demonstrated with two responsive hydrogel preparations, one where swelling is influenced by system pH, the other by changes in specific solute concentration.

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Authors and Affiliations

  1. Department of Chemistry, Shah Abdul Latif University, Khairpur, Pakistan

    M.H. Noomrio

  2. Department of Chemical Engineering, University of Bath, Claverton Down, Bath, BA2 7AY, UK

    R. Zhang & J. Hubble

  3. Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath, BA2 7AY, UK

    R. Eisenthal

Authors
  1. M.H. Noomrio
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  2. R. Zhang
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  3. R. Eisenthal
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  4. J. Hubble
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Correspondence to J. Hubble.

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Noomrio, M., Zhang, R., Eisenthal, R. et al. Characterisation of Hydrogel Gel Swelling by Molecular Exclusion. Biotechnol Lett 27, 1587–1590 (2005). https://doi.org/10.1007/s10529-005-1801-2

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  • DOI: https://doi.org/10.1007/s10529-005-1801-2

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