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Evaluation of the Influence of the Amplitude of the Second Phase of the Depolarizing Bipolar Half-Sinusoidal Defibrillation Pulse on Its Energy Efficiency

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Biomedical Engineering Aims and scope

Data obtained by modeling the responses of cardiomyocytes in a state of simulated fi brillation to bipolar depolarizing half-sinusoidal defibrillation pulses with different second-phase relative amplitudes were used to construct plots of the relationship between the proportion of the fi brillation cycle in which the defibrillation pulse caused long-lasting lengthening of the cardiomyocyte refractory period (the defibrillation completeness index) and defibrillation pulse energy. These plots showed that bipolar defibrillation pulses provide greater defibrillation completeness indices at lower energy than monopolar pulses.

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References

  1. Ten Tusscher, K. H. and Panfilov, A. V., "Alternans and spiral breakup in a human ventricular tissue model," Am. J. Physiol. Heart Circul. Physiol., 291, No. 3, H1088-H1100 (2006).

    Article  Google Scholar 

  2. Antonioletti, M., Biktashev, V. N., Jackson, A., Kharche, S. R., Stary, T., and Biktasheva, I. V., "BeatBox — HPC simulation environment for biophysically and anatomically realistic cardiac electrophysiology," PLoS One, 12, No. 5, Article ID e0172292 (2017).

  3. Gorbunov, B. B., "Study of the impact of rectangular current pulses on the Ten Tusscher–Panfilov model of human ventricular myocyte," J. Biomed. Sci. Eng., 10, No. 7, 355–366 (2017).

    Article  Google Scholar 

  4. Sweeney, R. J., Gill, R. M., Steinberg, M. I., and Reid, P. R., "Ventricular refractory period extension caused by defibrillation shocks," Circulation, 82, No. 3, 965–972 (1990).

    Article  CAS  PubMed  Google Scholar 

  5. Sweeney, R. J., Gill, R. M., and Reid, P. R., "Characterization of refractory period extension by transcardiac shock," Circulation, 83, No. 6, 2057–2066 (1991).

    Article  CAS  PubMed  Google Scholar 

  6. Dillon, S. M., "Optical recordings in the rabbit heart show that defibrillation strength shocks prolong the duration of depolarization and the refractory period," Circ. Res., 69, No. 3, 842–856 (1991).

    Article  CAS  PubMed  Google Scholar 

  7. Tovar, O. H. and Jones, J. L., "Relationship between 'extension of refractoriness' and probability of successful defi brillation," Am. J. Physiol., 272, No. 2, Part 2, H1011–H1019 (1997).

  8. Gorbunov, B. B., Vostrikov, V. A., Nesterenko, I. V., and Telyshev, D. V., "Areas of effectiveness of defibrillating pulse in the energy/phase diagram for the fibrillation cycle on the cardiomyocyte model," Int. J. Bioelectromagn., 20, No. 1, 1–4 (2018).

    Google Scholar 

  9. Gorbunov, B. B. and Selishchev, S. V., "Reactions to a hyperpolarizing pulse in model cardiomocytes exposed to fibrillation," Med. Tekh., No. 2, 5–8 (2019).

  10. Gorbunov, B. B., Nesterenko, I. V., Telyshev, D. V., and Selishchev, S. V., "Areas of eff ectiveness of half-sinusoidal monopolar and bipolar depolarizing defibrillation pulses on the energy diagram/phase of the fi brillation cycle," Ural Radio Eng. J., 5, No. 4, 369–379 (2021).

    Article  Google Scholar 

  11. Gorbunov, B. B., Vostrikov, V. A., Galyastov, A. A., and Telyshev, D. V., "The dependence of the fi brillation cycle fraction on which the defi brillation pulse is eff ective on the pulse energy," in: 2020 IEEE Conference of Russian Young Researchers in Electrical and Electronic Engineering (EIConRus), St. Petersburg and Moscow, Russia (2020), pp. 2486–2489.

  12. Gorbunov, B. B., Vostrikov, V. A., Galyastov, A. A., Nesterenko, I. V., Telyshev, D. V., and Denisov, M. V., "Guaranteed defibrillation on a cardiomyocyte model," in: 2020 Ural Symposium on Biomedical Engineering, Radioelectronics and Information Technology (USBEREIT), IEEE, (2020), pp. 0058–0061.

  13. GNU Octave: Scientifi c Programming Language; https://www.gnu.org/software/octave/ (2023).

  14. Gorbunov, B. B., Nesterenko, I. V., and Selishchev, S. V., "Evaluation of the influence of the second phase amplitude of the depolarizing biphasic half-sinusoidal defibrillation pulse on its energy efficiency: Supplementary resources" (2023); https://www.Researchgate.net/publication/367964962.

  15. Angelakos, E. T. and Torres, J. C., "The efficiency of electrical pulses for cardiac stimulation," Cardiologia (Basel), 44, No. 6, 355–365 (1964).

    Article  CAS  PubMed  Google Scholar 

  16. Koning, G., Schneider, H., Hoelen, A. J., and Reneman, R. S., "Amplitude-duration relation for direct ventricular defibrillation with rectangular current pulses," Med. Biol. Eng., 13, No. 3, 388–395 (1975).

    Article  CAS  PubMed  Google Scholar 

  17. Vostrikov, V. A. and Bogushevich, M. S., "Influence of the amplitude of the 2nd phase of bipolar sinusoidal impulses on the effectiveness of external defibrillation of the ventricles of the heart," Byull. Éksp. Biol. Med., 129, Supplement No. 2, 40–41 (2000).

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Correspondence to B. B. Gorbunov.

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Translated from Meditsinskaya Tekhnika, Vol. 57, No. 2, March–April, 2023, pp. 14–16

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Gorbunov, B.B., Nesterenko, I.V. & Selishchev, S.V. Evaluation of the Influence of the Amplitude of the Second Phase of the Depolarizing Bipolar Half-Sinusoidal Defibrillation Pulse on Its Energy Efficiency. Biomed Eng 57, 94–96 (2023). https://doi.org/10.1007/s10527-023-10276-w

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