Skip to main content

A History of the Discovery of the Hoorweg–Weiss–Lapicque Law

Biomedical Engineering volume 52, pages 357–360 (2019)Cite this article

First quantitative studies of the effect of electricity on excitable biological tissues forming the basis of the Hoorweg–Weiss–Lapicque law are described. The contribution of each researcher to the discovery is delineated and the practical significance of the Hoorweg–Weiss–Lapicque law is explained.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

USD 39.95

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

References

  1. Hoorweg, J. L., “Condensatorentladung und Auseinandersetzung mit du Bois-Reymond,” Pflügers Archiv, 52, 87-108 (1892).

    Article  Google Scholar 

  2. Irnich, W., “The fundamental law of electrostimulation and its application to defibrillation,” Pac. Clin. Electrophysiol., 13, No. 11, 1433-1447 (1990).

    Article  Google Scholar 

  3. Weiss, G., “Sur la possibilité de rendre comparables entre eux les appareils servant а l’excitation électrique,” Archives Italiennes de Biologie, 35, 413-446 (1901).

    Google Scholar 

  4. Irnich, W., “Georges Weiss’ fundamental law of electrostimulation is 100 years old,” Pac. Clin. Electrophysiol., 25, No. 2, 245-248 (2002).

    Article  Google Scholar 

  5. Blondel, A., “Oscillographes; nouveaux appareils pour l’étude des oscillations électriques lentes,” Comptes rendus hebdomadaires des séances de l’Académie des sciences, 116, 502-506 (1893).

    Google Scholar 

  6. Lapicque, L., “Recherches quantitatives sur l’excitation électrique des nerfs traitée comme une polarisation,” Journal de physiologie et de pathologie générale, 9, 620-635 (1907).

    Google Scholar 

  7. Brunel, N. and van Rossum, M. C., “Lapicque’s 1907 paper: From frogs to integrate-and-fire,” Biol. Cybern., 97, No. 5, 337-339 (2007).

  8. Blair, H. A., “On the intensity-time relations for stimulation by electric currents. I,” J. Gen. Physiol., 15, 709-729 (1932).

    Article  Google Scholar 

  9. Blair, H. A., “On the intensity-time relations for stimulation by electric currents. II,” J. Gen. Physiol., 15, 731-755 (1932).

    Article  Google Scholar 

  10. Lapicque, L., “Définition expérimentale de l’excitabilité,” Comptes rendus des séances de la Société de biologie et de ses filiales, 67, 280-283 (1909).

    Google Scholar 

  11. Gorbunov, B. B., “A study of the myocardium cell membrane using the Luo−Rudy model,” Biomed. Eng., 46, 117-119 (2012).

    Article  Google Scholar 

  12. Gurvich, N. L. and Yun’ev, G. S., “On recovery of normal activity of fibrillating heart in warm-blooded animals by a capacitor discharge,” Byul. Eksp. Biol. Med., 8, No. 1, 55-58 (1939).

    Google Scholar 

  13. Gurvich, N. L., “The importance of the physical characteristics of capacitor discharge in recovering normal activity of fibrillating heart,” in: Abstracts of Works of Biology Division of the Academy of Sciences of the USSR for 1940, Izd. Akademii Nauk SSSR, Moscow (1941), pp. 375-376.

Download references

Author information

Authors and Affiliations

  1. Institute of Biomedical Systems, National Research University of Electronic Technology (MIET), Zelenograd, Moscow, Russia

    B. B. Gorbunov, I. V. Nesterenko & D. V. Telyshev

  2. V. A. Negovsky Research Institute of General Reanimatology, Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia

    V. A. Vostrikov

  3. Institute of Bionic Technologies and Engineering, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Moscow, Russia

    D. V. Telyshev

Authors
  1. B. B. Gorbunov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. A. Vostrikov
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. I. V. Nesterenko
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. D. V. Telyshev
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to B. B. Gorbunov.

Additional information

Translated from Meditsinskaya Tekhnika, Vol. 52, No. 5, Sep.-Oct., 2018, pp. 48-50.

Rights and permissions

Reprints and Permissions

About this article

Verify currency and authenticity via CrossMark

Cite this article

Gorbunov, B.B., Vostrikov, V.A., Nesterenko, I.V. et al. A History of the Discovery of the Hoorweg–Weiss–Lapicque Law. Biomed Eng 52, 357–360 (2019). https://doi.org/10.1007/s10527-019-09847-7

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10527-019-09847-7