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A Device for Activation of Tissue Cell Proliferation by Dosed Exposure to Radio-Frequency Currents

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Biomedical Engineering Aims and scope

Activation of reducing processes in biological tissues by exposure to pulse-modulated radio-frequency (RF) currents is studied. It is shown that the weak destructive effect of RF currents activates the process of proliferation of healthy cells. A prototype device for dosed exposure to pulse-modulated RF currents based on needle electrodes is described. The results of experimental animal studies and randomized clinical studies using a purpose-designed prototype device for dosed exposure to pulse-modulated RF currents are presented. The clinical efficacy of dosed RF stimulation for treatment of purulent, inflammatory, and purulent-inflammatory processes is shown to be high.

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References

  1. Buckingham, M., “Myogenic progenitor cells and skeletal myogenesis in vertebrates,” Curr. Opin. Genet. Dev., 16, 525-532 (2006).

    Article  Google Scholar 

  2. Stocum, D. L., Regenerative Biology and Medicine, Acad. Press, New York (2006).

    Google Scholar 

  3. Frolov, S. A., Sushkov, O. I., Pshelenskaya, A. I., Danyleiko, Yu. K., Salyuk, V. A., and Belov, S. V., “Experimental substantiation of the parameters of electrostimulation of processes of open surgical wound healing,” Koloproktol., No. 2 (44), 9-18 (2013).

    Google Scholar 

  4. Balan, O. V., Belov, S. V., Danyleiko, Yu. K., Dubovaya, T. K., Markitantova, Yu. V., Osiko, V. V., Salyuk, V. A., Suhorukov, V. S., and Ozernyuk, N. D., “Activation of repair processes in rat tissues by exposure to periodic pulse-modulated radio-frequency current,” Izv. Ros. Akad. Nauk. Ser, Biol., No. 6, 645-652 (2010).

    Google Scholar 

  5. Balan, O. V., Analysis of in vitro Differentiation of Satellite Cells and Myoblasts Extracted from Skeletal Muscles of Rats at Various Stages of Ontogenesis: Candidate’s Thesis [in Russian], IBR RAN, Moscow (2009).

    Google Scholar 

  6. Pshelenskaya, A. I., Use of High-Frequency Electrostimulation for Treatment of Open Wounds in the Pubic and Sacrococcygeal Regions: Candidate’s Thesis [in Russian], GNTs Koloproktologii, Moscow (2014).

    Google Scholar 

  7. Frolov, S. A., Sushkov, O. I., Maksimova, L. V., Pshelenskaya, A. I., Belov, S. V., Danyleiko, Yu. K., Osiko, V. V., and Salyuk, V. A., “High-frequency electrostimulation of the wound process in patients after surgical treatment of perianal fistula and pilonidal cyst,” Koloproktol., No. 3 (44), 3-7 (2010).

    Google Scholar 

  8. Baburin, N. V., Belov, S. V., Danyleiko, Yu. K., Egorov, A. B., Lebedeva, T. P., Nefedov, S. M., Osiko, V. V., and Salyuk, V. A., “Heterogeneous recombination in water vapor plasma as a mechanism of action on biological tissues,” DAN, 426, No. 4, 1-3 (2009).

    Google Scholar 

  9. Belov, S. V., Danyleiko, Yu. K., Nefedov, S. M., Osiko, V. V., Salyuk, V. A., and Sidorov, V. A., “Specific features of generation of low-temperature plasma in high-frequency plasma electrosurgical apparatuses,” Med. Tekh., No. 2, 26-32 (2011).

    Google Scholar 

  10. Balan, O. V., Markitantova, Y. V., Ozernnyuk, N. D., Belov, S. V., Danileiko, Y. K., Osiko, V. V., Salyuk, V. A., Dubovaya, T. K., and Suhorukov, V. S., “Activation of reconstructive processes in rat tissues under the action of radiofrequency current with a periodic impulse mode of modulation,” Biology Bulletin, 37, No. 6, 551-557 (2010).

    Article  Google Scholar 

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Correspondence to S. V. Belov.

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Translated from Meditsinskaya Tekhnika, Vol. 52, No. 2, Mar.-Apr., 2018, pp. 6-9.

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Belov, S.V., Danyleiko, Y.K., Osiko, V.V. et al. A Device for Activation of Tissue Cell Proliferation by Dosed Exposure to Radio-Frequency Currents. Biomed Eng 52, 80–83 (2018). https://doi.org/10.1007/s10527-018-9787-y

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  • DOI: https://doi.org/10.1007/s10527-018-9787-y

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