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Natural anti-aging skincare: role and potential

Abstract

The deterioration of the skin morphology and physiology is the first and earliest obvious harbinger of the aging process which is progressively manifested with increasing age. Such deterioration affects the vital functions of the skin such as homeodynamic regulation of body temperature, fluid balance, loss of electrolytes and proteins, production of vitamin D, waste removal, immune surveillance, sensory perception, and protection of other organs against deleterious environmental factors. There are, however, harmful chemicals and toxins found in everyday cosmetics that consumers are now aware of. Thus, the natural beauty industry is on the rise with innovative technology and high-performance ingredients as more consumers demand healthier options. Therefore, the aims of this review are to give some critical insights to the effects of both intrinsic and extrinsic factors on excessive or premature skin aging and to elaborate on the relevance of natural beauty and natural anti-aging skincare approaches that will help consumers, scientists and entrepreneurs make the switch. Our recent investigations have shown the potential and relevance of identifying more resources from our rich natural heritage from various plant sources such as leaves, fruits, pomace, seeds, flowers, twigs and so on which can be explored for natural anti-aging skincare product formulations. These trending narratives have started to gain traction among researchers and consumers owing to the sustainability concern and impact of synthetic ingredients on human health and the environment. The natural anti-aging ingredients, which basically follow hormetic pathways, are potentially useful as moisturizing agents; barrier repair agents; antioxidants, vitamins, hydroxy acids, skin lightening agents, anti-inflammatory ingredients, and sunblock ingredients.

Graphic abstract

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Fig. 1
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Abbreviations

MMP:

Matrix metalloproteinases

Cav-1:

Caveolin-1

NLCS:

Nanostructured lipid carriers

UVB:

Ultraviolet B

SPF:

Sun protecting factor

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Acknowledgements

No funding was provided for this research. The Centre for Natural Products Research and Drug Discovery (CENAR), and the Research Management & Innovation Complex, University of Malaya, Kuala Lumpur are, however, greatly acknowledged.

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IAA and MAM were involved in the review conceptualization and first draft of the manuscript. IAA, MAM, NHZ and AHA were involved in the first review and subsequent completion of the review. All the authors were then involved in the critical review of the manuscript, final review and editing.

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Correspondence to Idris Adewale Ahmed.

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The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Ahmed, I.A., Mikail, M.A., Zamakshshari, N. et al. Natural anti-aging skincare: role and potential. Biogerontology 21, 293–310 (2020). https://doi.org/10.1007/s10522-020-09865-z

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Keywords

  • Aging
  • Anti-aging
  • Homeodynamic
  • Hormesis
  • Hormetins
  • Skincare
  • Natural beauty