The NLSY Kinship Links: Using the NLSY79 and NLSY-Children Data to Conduct Genetically-Informed and Family-Oriented Research
- 326 Downloads
The National Longitudinal Survey of Youth datasets (NLSY79; NLSY-Children/Young Adults; NLSY97) have extensive family pedigree information contained within them. These data sources are based on probability sampling, a longitudinal design, and a cross-generational and within-family data structure, with hundreds of phenotypes relevant to behavior genetic (BG) researchers, as well as to other developmental and family researchers. These datasets provide a unique and powerful source of information for BG researchers. But much of the information required for biometrical modeling has been hidden, and has required substantial programming effort to uncover—until recently. Our research team has spent over 20 years developing kinship links to genetically inform biometrical modeling. In the most recent release of kinship links from two of the NLSY datasets, the direct kinship indicators included in the 2006 surveys allowed successful and unambiguous linking of over 94 % of the potential pairs. In this paper, we provide details for research teams interested in using the NLSY data portfolio to conduct BG (and other family-oriented) research.
KeywordsNLSY79 NLSYC NLSY97 Behavior genetics Biometrical modeling Siblings Kinship links Cousins
Three grants from the National Institutes of Health (NICHD) have supported the work described within this paper: in the 1990s, R01-HD21973; in 2003–2007 RO1-HD043265; in 2012–2014, R01-HD065865 (Joseph Lee Rodgers was PI on each grant). The authors express appreciation to the Bureau of Labor Statistics and the National Opinion Research Center for longstanding expertise in conceptualizing, funding, and collecting the NLSY data. Particular appreciation is expressed to many individuals at the Center for Human Resource Research at Ohio State for expert management of the NLSY data, and more specifically for conceptual, statistical, and data management support of past NLSY kinship linking efforts. Those individuals at CHRR include Randy Olsen, Elizabeth Cooksey, Frank Mott, Paula Baker, Steven McClaskie, and Karima Nagy. The co-authors on this paper are those who have contributed to coding or conceptualizing the NLSY kinship links since the original linking projects in the early 1990s; with the exception of van den Oord, who developed his own code for NLSYC kinship links, each co-author has been financially supported on one or more of the NIH grants listed above.
Compliance with ethical standards
Conflict of Interest
The authors declare that they have no conflict of interest.
Human and Animal Rights and Informed Consent
This article does not contain any studies with human or animal subjects performed by the any of the authors.
- Baydar N, Greek A (2001) Analysis of data from related individuals. Working paper, Battell Centers for Public Health Research and Evaluation, SeattleGoogle Scholar
- D’Onofrio BM, Rickert ME, Langstrom N, Donahue KL, Coyne CA, Larsson H, Ellingson JM, Van Hulle CA, Iliadou AN, Rathouz PJ, Lahey BB, Lichtenstein P (2012) Familial confounding of the association between maternal smoking during pregnancy and offspring substance use and problems: converging evidence across samples and measures. Arch Gen Psychiatry 69:1140–1150CrossRefPubMedPubMedCentralGoogle Scholar
- Doughty D, Rodgers JL (2000) Behavior genetic modeling of menarche in U.S. females. In: Rodgers JL, Rowe DC, Miller WB (eds) Genetic influences on fertility and sexuality. Kluwer Academic Press, BostonGoogle Scholar
- Goodnight JA, D’Onofrio BM, Cherlin AJ, Emery RE, Van Hulle CA, Lahey BB (2013) Effects of multiple maternal relationship transitions on offspring antisocial behavior in childhood and adolescence: a cousin-comparison analysis. J Abnorm Child Psychol 41:185–198CrossRefPubMedPubMedCentralGoogle Scholar
- Green DM, Swets JA (1966) Signal detection theory and psychophysics. Wiley, New YorkGoogle Scholar
- Lahey BB, Van Hulle CA, Rathouz PJ, Rodgers JL, D’Onofrio BM, Waldman ID (2009) Are oppositional-defiant and hyperactive-inattentive symptoms developmental precursors to conduct problems in late childhood?: genetic and environmental links. J Abnorm Child Psychol 37:45–58CrossRefPubMedPubMedCentralGoogle Scholar
- Lai C-Q (2006) How much of human height is genetic and much is due to nutrition? Scientific AmericanGoogle Scholar
- Neale MC, Hunter MD, Pritikin JN, Zahery M, Brick TR, Kickpatrick RM, Estabrook R, Bates TC, Maes HH, Boker SM (2015) OpenMx 2.0: extended structural equation and statistical modeling. Psychometrika. 10.1007/s11336-014-9435-8
- Rodgers JL (1996) NLSY Youth linking algorithm. Unpublished manuscript, Department of Psychology, University of OklahomaGoogle Scholar
- Shadish WR, Cook TD, Campbell DT (2002) Experimental and quasi-experimental designs for generalized causal inference. Houghton Mifflin, BostonGoogle Scholar
- Visscher PM, Medland SE, Ferreira MAR, Morley KI, Zhu G, Cornes BK, Montgomery GW, Martin NG (2006) Assumption-free estimation of heritability from genome-wide identity-by-descent sharing between full siblings. PLoS Genet 2(e41):316–325Google Scholar