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Anti-SARS-CoV-2 Activity of a Polyphenolic Complex from Maackia amurensis

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We studied the ability of the polyphenolic complex from Maackia amurensis, the active substance of Maksar, to inhibit the cytopathogenic effect induced by the SARS-CoV-2 and to reduce the concentration of viral RNA in infected Vero E6 cells. Polyphenolic complex showed significant anti-SARS-CoV-2 activity and effectively inhibited viral replication by direct action on viral particles and the early stage of viral infection.

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Authors and Affiliations

  1. G. P. Somov Research Institute of Epidemiology and Microbiology, Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Vladivostok, Russia

    N. V. Krylova, O. V. Iunikhina, A. B. Pott, E. V. Persiyanova & M. Y. Shchelkanov

  2. G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far East Division of the Russian Academy of Sciences, Vladivostok, Russia

    S. A. Fedoreev, N. P. Mishchenko & D. V. Tarbeeva

Authors
  1. N. V. Krylova
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  2. O. V. Iunikhina
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  3. S. A. Fedoreev
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  4. A. B. Pott
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  5. E. V. Persiyanova
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  6. N. P. Mishchenko
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  7. D. V. Tarbeeva
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  8. M. Y. Shchelkanov
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Corresponding author

Correspondence to N. V. Krylova.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 176, No. 8, pp. 216-219, August, 2023

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Krylova, N.V., Iunikhina, O.V., Fedoreev, S.A. et al. Anti-SARS-CoV-2 Activity of a Polyphenolic Complex from Maackia amurensis. Bull Exp Biol Med 176, 187–190 (2023). https://doi.org/10.1007/s10517-024-05992-6

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  • DOI: https://doi.org/10.1007/s10517-024-05992-6

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