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Experimental Model for the Study of Reparative Bone Regeneration in the Reconstruction of the Lower Jaw

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An experimental in vivo model has been developed on the rabbit mandible to study reparative regeneration of alveolar bone after intercortical split osteotomy and the role of the periosteum in the process of reparative osteogenesis. The peculiarity of this model is fixation of the periosteum over the reconstruction zone, which allows preserving the bone block displaced during surgery and leads to the formation of an organotypic structure of the regenerate with cortical and spongy bone.

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Authors and Affiliations

  1. Peoples’ Friendship University of Russia (RUDN University), Moscow, Russia

    A. A. Muraev, A. V. Volkov & S. Yu. Ivanov

  2. Central Clinical Hospital with Clinic of the Office of the President of the Russian Federation, Moscow, Russia

    V. V. Polevoi

  3. N. N. Burdenko General Military Clinical Hospital, Ministry of Defense of the Russian Federation, Moscow, Russia

    S. V. Tereshchyuk

  4. I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation (Sechenov University), Moscow, Russia

    S. V. Tereshchyuk, A. M. Gusarov, P. P. Soloshenkov & S. Yu. Ivanov

Authors
  1. A. A. Muraev
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  2. A. V. Volkov
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  3. V. V. Polevoi
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  4. S. V. Tereshchyuk
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  5. A. M. Gusarov
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  6. P. P. Soloshenkov
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  7. S. Yu. Ivanov
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Correspondence to A. A. Muraev.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 175, No. 2, pp. 256-260, February, 2023

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Muraev, A.A., Volkov, A.V., Polevoi, V.V. et al. Experimental Model for the Study of Reparative Bone Regeneration in the Reconstruction of the Lower Jaw. Bull Exp Biol Med 175, 286–290 (2023). https://doi.org/10.1007/s10517-023-05851-w

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  • DOI: https://doi.org/10.1007/s10517-023-05851-w

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