The significance of Yersinia pestis surface antigens in adhesiveness to specific bacteriophages has been studied with the use of two methodological approaches. It was shown that Ail protein immobilized on the surface of polystyrene microspheres (but not in the solution), can bind both the Pokrovskaya phage and pseudotuberculous diagnostic phage. YapF autotransporter interacted with both phages in a water-soluble form, but YapF bound to polystyrene microspheres interacted only with the Pokrovskaya phage. An assumption was made that Ail and YapF proteins can be the primary receptors providing non-specific reversible binding to the phages used in this work.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 174, No. 8, pp. 207-211, August, 2022
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Byvalov, A.A., Dudina, L.G., Ivanov, S.A. et al. Yersinia pestis Surface Antigens in Reception of Specific Bacteriophages. Bull Exp Biol Med 174, 241–245 (2022). https://doi.org/10.1007/s10517-023-05681-w
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DOI: https://doi.org/10.1007/s10517-023-05681-w