In patients with schizophrenia, the thermal balance of the cerebral cortex was studied by means of microwave radiothermometry method and compared with the markers of systemic inflammation and clinical features of the disease course during therapy. Low temperature heterogeneity of the cerebral cortex was associated with an increase in the activity of inflammatory markers in the blood and, in most cases, with a positive response to therapy. High temperature heterogeneity of the cerebral cortex was typical of patients with insufficient activity of the inflammatory proteolytic system, high levels of antibodies to brain antigens, a more severe course of the disease and, in most cases, with resistance to therapy. A conclusion was made about the diagnostic value of the study of the thermal balance of the brain in patients with schizophrenia.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 173, No. 4, pp. 522-526, April, 2022
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Zozulya, S.A., Shevelev, O.A., Tikhonov, D.V. et al. Thermal Balance of the Brain and Markers of Inflammatory Response in Patients with Schizophrenia. Bull Exp Biol Med 173, 505–509 (2022). https://doi.org/10.1007/s10517-022-05571-7
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DOI: https://doi.org/10.1007/s10517-022-05571-7