Skip to main content
SpringerLink
Log in

Condition of Adrenergic Innervation Apparatus of the Thyroid Gland, Blood and Lymph Vessels, and Lymph Nodes during Correction of Hypothyrosis

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

We used specific histochemical fluorescence-microscopic method of visualization of catecholamines to study adrenergic innervation of the thyroid gland tissue, blood vessels of the thyroid gland, cervical lymphatic vessel and lymph nodes in rats during correction of hypothyroidism with a bioactive formulation (Vozrozhdenie Plus balm with Potentilla alba L.). In experimental hypothyroidism, adrenergic innervation of the thyroid gland and the wall of the cervical lymph node, concentrated mainly along the arterial vessels and the cervical lymphatic vessel, retained its structural formations (plexuses and varicosities), but diffusion of catecholamines outside these formations was observed. Correction with the bioactive formulation restored of the contours of the nerve plexuses and varicosities and their brighter fluorescence in the thyroid gland and cervical lymphatic vessel and node. During correction of hypothyroidism with the bioactive formulation, reorganization of regional lymphatic vessels and nodes was more pronounced than reorganization of the thyroid gland.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Arkhipova EV, Shantanova LN, Mondodoev AG. Thyrotropic properties of potentilla alba L. Vestn. Buryat. Gos. Univer. 2014;(12):118-122. Russian.

    Google Scholar 

  2. Balakirev NA, Deltsov AA, Maksimov VI, Kozlov SA, Staroverova IN. Behavioral activity of rats in experimental hyperotherosis, and its correction with iodine-containing preparations. Ross. Sel’skokhoz. Nauka. 2019;(1):58-61.doi: 10.31857/S2500-26272019158-61. Russian.

  3. Borodin YuI, Gorchakova OV, Sukhovershin AV, Gorchakov VN, Fartukov AV, Kolmogorov YuP, Demchenko GA. The Concept of the Lymphatic Region in Preventive Lymphology. Novosibirsk, 2018. Russian.

  4. Gorchakova OV, Gorchakov VN, Demchenko GA, Abdreshov SN. Morphological characteristics of tissue microregion of the thyroid gland at experimental hypothyroidism. Sib. Nauch. Med. Zh. 2019;39(4):46-54. doi: 10.15372/SSMJ20190406. Russian.

  5. Gorchakova OV, Melnikova EV, Gorchakov VN. Phyto-optimization of the structure and function of the lymph node in conditions of rehabilitation of the consequences of hypothyroidism. Prakt. Fitoter. 2009;(1):12-17. Russian.

    Google Scholar 

  6. Zykov AA, Golovnev VA. Pharmacological Regulation of the Lymphatic System. Novosibirsk, 2002. Russian.

  7. Kamilov‘ FKh, Mamtsev AN, Kozlov VN, Abdullina GM, Lobyreva OV. Activity of antioxidant enzymes and processes of free radical oxidation in experimental hypothyroidism and correction of thyroid shifts with iodized polysaccharide complexes. Kazan. Med. Zh. 2012;93(1):116-119. Russian.

  8. Kozlov VN. Thyroid transformation at modeling endemic effect of white rats under experiment. Sib. Med. Zh. 2006;63(5):27-30. Russian.

    Google Scholar 

  9. Lychkova AE. Nervous regulation of thyroid function. Vestn. Ross. Akad. Med. Nauk. 2013;(6):49-55.doi: 10.15690/vramn.v68i6.673. Russian.

  10. Usenova GS, Sinyavskii YuA. Patent of Republic of Kazakhstan No. 21772. Biological active food additive balsam Vozrozhdenie Plus. Bull. No. 10. Published October 15, 2009. Rusisan.

  11. Abdreshov SN, Akhmetbaeva NA, Atanbaeva GK, Mamataeva AT, Nauryzbai UB. Adrenergic innervations of the thyroid gland, blood and lymph vessels, and lymph nodes in hypothyroidism. Bull. Exp. Biol. Med. 2019;168(2):295-299. doi: https://doi.org/10.1007/s10517-019-04694-8

    Article  CAS  PubMed  Google Scholar 

  12. Abdreshov SN, Demchenko GА, Bulekbaeva LE, Nurmakhanova BА, Nauryzbai UB, Koganezawa UN. Changes of the thyroid hormones concentration and the biochemical parameters feautures of lymph and blood of rat with hypothyroidism. News Natl Acad. Sci. Republic of Kazakhstan. Ser. Biol. Med. 2018;6:30-36. https://doi.org/10.32014/2018.2518-1629.14

    Article  Google Scholar 

  13. Kim B, Carvalho-Bianco SD, Larsen PR. Thyroid hormone and adrenergic signaling in the heart. Arq. Bras. Endocrinol. Metabol. 2004;48(1):171-175. doi: https://doi.org/10.1590/s0004-27302004000100019

    Article  PubMed  Google Scholar 

  14. Sundler F, Grunditz T, Håkanson R, Uddman R. Innervation of the thyroid. A study of the rat using retrograde tracing and immunocytochemistry. Acta Histochem. Suppl. 1989;37:191-198.

    CAS  Google Scholar 

  15. Young JB, Bürgi-Saville ME, Bürgi U, Landsberg L. Sympathetic nervous system activity in rat thyroid: potential role in goitrogenesis. Am. J. Physiol. Endocrinol. Metab. 2005;288(5):E861-E867. doi: https://doi.org/10.1152/ajpendo.00292.2004

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratory of Physiology of the Lymphatic System, Institute of Human and Animal Physiology, Science Committee, Ministry of Education and Science, Republic of Kazakhstan, Almaty, Republic of Kazakhstan

    S. N. Abdreshov, G. A. Demchenko, A. T. Mamataeva, N. A. Akhmetbaeva, U. N. Kozhaniyazova & U. B. Nauryzbai

  2. Al-Farabi Kazakh National University, Almaty, Kazakhstan

    G. K. Atanbaeva & S. A. Mankibaeva

Authors
  1. S. N. Abdreshov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. A. Demchenko
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. T. Mamataeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. K. Atanbaeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. S. A. Mankibaeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. N. A. Akhmetbaeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. U. N. Kozhaniyazova
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. U. B. Nauryzbai
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to S. N. Abdreshov.

Additional information

Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 171, No. 2, pp. 253-258, February, 2021

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Abdreshov, S.N., Demchenko, G.A., Mamataeva, A.T. et al. Condition of Adrenergic Innervation Apparatus of the Thyroid Gland, Blood and Lymph Vessels, and Lymph Nodes during Correction of Hypothyrosis. Bull Exp Biol Med 171, 281–285 (2021). https://doi.org/10.1007/s10517-021-05212-5

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10517-021-05212-5

Key Words

Search

Navigation