The experiments on narcotized male rats (n=30) determined the parameters of passive and active pulsatile modes of isolated segment of femoral artery in situ. Rheographic elasticity (RE) and reactivity (RR) were correspondingly determined as the ratios of peak-to-peak (p2p) magnitudes of passive and active pulsatile oscillations of arterial electroimpedance (AEI) to p2p magnitude of BP undulations. The medians and interquartile ranges of RE and RR were 6 (3; 11) and 70 (40; 110) mΩ/mm Hg, respectively. The maximal and minimal values of RE and RR in various rats differed by 50 and 80 times, respectively, and were bimodally distributed: in major group (n=23), the values were RE<15 and RR<200 mΩ/mm Hg, whereas in minor group (n=7), these parameters were RE>20 and RR>300 mΩ/mm Hg. The above ranges of RE and RR parameters were considered as the diagnostic signs of normal and pseudo-healthy rats with pathologically augmented AEI oscillations, respectively. Statistical analysis of all rats (n=30) revealed the positive correlation between RE and RR (r=0.76) with linear regression RR=31+7.6×RE. It is hypothesized that this correlation is underlain by a mechanism similar to that described by the Frank—Starling law for myocardium.
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References
Markosyan TG, Alyaev YG, Glybochko PV, Kirpatovsky VI, Mudraya IS, Nikitin SS, Popov EG, Revenko SV. Rhythmic oscillations of human penile bioimpedance in healthy individuals and in patients with vascular erectile dysfunction. Bull. Exp. Biol. Med. 2011;151(4):405-410. doi: https://doi.org/10.1007/s10517-011-1342-8.
Nesterov AV, Gavrilov IY, Selector LY, Mudraya IS, Revenko SV. Fourier analysis of human finger bioimpedance variances. Bull. Exp. Biol. Med. 2010;150(1):26-31. doi: https://doi.org/10.1007/s10517-010-1059-0
Glybochko PV, Aljaev JG, Grigorjan VA, Markosjan TG, Revenko SV, Nikitin SS, Mudraja IS, Limonov EV. Patent RU No. 2444989. Method of diagnosing vasculogenic erectile dysfunction. Bull. No. 8. Published March 20, 2012.
Revenko SV. Rheography: harmonic perspectives. Nervn.-Mysherch. Bol. 2012;(4):8-19. Russian.
Revenko SV, Tikhomirova LN, Gavrilov IY, Tarakanov IA. Effect of Alternating Electric Current on Pulsation Mode of Rat Major Arteries In Situ. Bull. Exp. Biol. Med. 2019;167(3):305-310. doi: https://doi.org/10.1007/s10517-019-04515-y
Revenko SV, Tikhomirova LN, Nesterov AV, Tarakanov IA. Bimodal Electrical Properties of Rat Major Artery Segment In Situ. Bull. Exp. Biol. Med. 2018;164(6):701-706. doi: https://doi.org/10.1007/s10517-018-4062-5
Barker AL, Konopatskaya O, Neal CR, Macpherson JV, Whatmore JL, Winlove CP, Unwin PR, Shore AC. Observation and characterisation of the glycocalyx of viable human endothelial cells using confocal laser scanning microscopy. Phys. Chem. Chem. Phys. 2004;6(5):1006-1011.
Ebong EE, Macaluso FP, Spray DC, Tarbell JM. Imaging the endothelial glycocalyx in vitro by rapid freezing/freeze substitution transmission electron microscopy. Arterioscler. Thromb. Vasc. Biol. 2011;31(8):1908-1915. doi: https://doi.org/10.1161/ATVBAHA.111.225268
Grimnes S, Martinsen OG. Bioimpedance and Bioelectricity Basics. Amsterdam, 2008.
Jünemann KP, Scheepe J, Persson-Jünemann C, Schmidt P, Abel K, Zwick A, Tschada R, Alken P. Basic experimental studies on corpus cavernosum electromyography and smoothmuscle electromyography of the urinary bladder. World J. Urol. 1994;12(5):266-273. doi: https://doi.org/10.1007/BF00191206
Mano T, Iwase S, Toma S. Microneurography as a tool in clinical neurophysiology to investigate peripheral neural traffic in humans. Clin. Neurophysiol. 2006;117(11):2357-2384. doi: https://doi.org/10.1016/j.clinph.2006.06.002
Mudraya IS, Revenko SV, Nesterov AV, Gavrilov IY, Kirpatovsky VI. Bioimpedance harmonic analysis as a tool to simultaneously assess circulation and nervous control. Physiol. Meas. 2011;32(7):959-976. doi: https://doi.org/10.1088/0967-3334/32/7/S17
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 170, No. 12, pp. 698-703, December, 2020
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Tarakanov, I.A., Tikhomirova, L.N., Gavrilov, I.Y. et al. Relationship between Passive and Active Pulsations of Rat Artery as Vascular Extension of Frank—Starling Law. Bull Exp Biol Med 170, 719–723 (2021). https://doi.org/10.1007/s10517-021-05140-4
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DOI: https://doi.org/10.1007/s10517-021-05140-4