We studied the effect of 1- and 2-h exposure to low-frequency magnetic fields (0.3 and 0.42 mT) on the sensitivity of Pseudomonas aeruginosa to 18 antibiotics. P. aeruginosa samples were obtained from 20 patients with burns. Exposure to magnetic field reduced the resistance of P. aeruginosa and increased their susceptibility to antimicrobial drugs. This increase was positively correlated with field intensity and duration of exposure. After 2-h exposure to 0.42 mT, susceptibility of P. aeruginosa to antimicrobial drugs aztreonam, ceftazidime, colistin, imipenem, levofloxacin, and meropenem significantly increased. In addition, resensitization of P. aeruginosa to carbapenems, penicillin, quinolones, and aminoglycosides groups was observed.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 170, No. 7, pp. 45-49, July, 2020
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Al-Delaimi, M.S., Yacoob Aldosky, H.Y. Amending the Efficiency of Antimicrobials against Multidrug-Resistant Pseudomonas aeruginosa by Low-Frequency Magnetic Fields. Bull Exp Biol Med 170, 35–39 (2020). https://doi.org/10.1007/s10517-020-04999-z
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DOI: https://doi.org/10.1007/s10517-020-04999-z